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Ion Channels and Ion Pumps

Metabolic and Endocrine Relationships in Biology and Clinical Medicine

  • Book
  • © 1994

Overview

Editors:
  1. Piero P. Foà

    1. West Bloomfield, USA
      Department of Physiology, Wayne State University, Detroit, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Mary F. Walsh

    1. Section of Endocrinology,Department of Internal Medicine,School of Medicine, Wayne State University, Detroit, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Endocrinology and Metabolism (EAM, volume 6)

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Table of contents (25 chapters)

  1. Front Matter

    Pages i-xv
    Download chapter PDF

  2. The Molecular Structure and Gating of Calcium Channels

    • Susan M. J. Dunn, Manjunatha B. Bhat, A. Murat Öz
    Pages 1-18

  3. Calcium Signals in Cell Proliferation, Differentiation, and Death

    • James F. Whitfield
    Pages 19-58

  4. Role of Calcium in Stimulus-Secretion Coupling in Exocrine Glands

    • Catherine S. Chew
    Pages 59-90

  5. Calcium Channels, the Pancreatic Islet, and Endocrine Secretion

    • Joseph C. Dunbar
    Pages 91-97

  6. Calcium Channels in Cells of the Anterior Pituitary

    • David M. Lawson
    Pages 98-108

  7. Role of Calcium in the Secretion of Atrial Natriuretic Peptide

    • Mary F. Walsh
    Pages 109-115

  8. Intracellular Ca2+ and Insulin Action: Possible Role in the Pathogenesis of Syndrome X

    • Joseph Levy, James R. Sowers
    Pages 116-136

  9. [Ca2+]i and Contraction of Arterial Smooth Muscle

    • Christopher M. Rembold
    Pages 137-150

  10. Autoimmunity Against the Nicotinic Acetylcholine Receptor and the Presynaptic Calcium Channel at the Neuromuscular Junction

    • Angelo A. Manfredi, Maria Pia Protti, Matteo Bellone, Lucia Moiola, Bianca M. Conti-Tronconi
    Pages 151-189

  11. Clinical Pharmacology of Calcium Channels

    • Tore K. Uski, Edward D. HÖgestÄtt, Karl-Erik Andersson
    Pages 190-225

  12. Hormonal Modulation of Sodium Pump Activity: Identification of Second Messengers

    • Douglas R. Yingst
    Pages 226-240

  13. Endogenous Regulation of Sodium Pump Activity

    • Peter A. Doris
    Pages 241-260

  14. Structure, Gating, and Clinical Implications of the Potassium Channel

    • Gianfranco Prestipino, Mario Nobile, Egidio Maestrone
    Pages 261-281

  15. Potassium Channels in Skeletal Muscle

    • Ralf Weik
    Pages 282-316

  16. The Role of Potassium Ions in the Control of Heart Function

    • Fritz Markwardt
    Pages 317-348

  17. Nonrenal Potassium Homeostasis: Hypokalemia and Potassium Depletion—Role of Skeletal Muscle Potassium-Pump (Na+,K+- ATPase)

    • Keld Kjeldsen
    Pages 349-372

  18. The Clinical Pharmacology of Potassium Channels

    • P. N. Strong
    Pages 373-394

  19. Ion Transport in Vascular Smooth Muscle and the Pathogenesis of Hypertension

    • Christian Aaljæ, Keld Kjeldsen
    Pages 395-417

  20. Calcium Ion Homeostasis in the Aging Brain: Regulation of Voltage-Dependent Calcium Channels

    • Florenzo Battaini, Stefano Govoni, Maria Sandra Magnoni, Marco Trabucchi
    Pages 418-435
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Keywords

About this book

Omnis cellula e cellula, "every cell from a cell," was dogma to the 19th­ century cellular physiologist and the cornerstone of Virchow's Cellular­ pathologie. "Spread out a cell into a layer and you will find that, in ceasing to be a cell, it has ceased to act as such," wrote the British 1 physiologist G . R. Lewes more than a century age. "The cell remains vital as long as its wall remains intact . . . " keeping its content "pure and clear" and thus preserving the "vital principle" within, echoed Claude 2 Bernard a few years later. The notion of the cell membrane as a pro­ tecting envelope held sway until it became clear that it could not account for the "coalescence" of poorly differentiated embryonic "vesicles" and for their transformation into "cell-like structures" capable of auto­ regulation and yet subject to what the grandfather of one of us defined as the "federal obligations imposed by the whole organism. ,,3 A new concept was needed, and soon the membrane was described as a structure capable of uniting as well as separating adjacent cells. Morphologic evidence for this dual function was obtained several years later when the electron microscope revealed the existence of tight and gap junc­ tions which, acting as intercellular bonds and channels, allowed the cells to communicate with one another and thus coordinate their biologic activities.

Editors and Affiliations

  • West Bloomfield, USA

    Piero P. Foà

  • Department of Physiology, Wayne State University, Detroit, USA

    Piero P. Foà

  • Section of Endocrinology,Department of Internal Medicine,School of Medicine, Wayne State University, Detroit, USA

    Mary F. Walsh

Bibliographic Information

  • Book Title: Ion Channels and Ion Pumps

  • Book Subtitle: Metabolic and Endocrine Relationships in Biology and Clinical Medicine

  • Editors: Piero P. Foà, Mary F. Walsh

  • Series Title: Endocrinology and Metabolism

  • DOI: https://doi.org/10.1007/978-1-4612-2596-6

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag New York, Inc. 1994

  • Hardcover ISBN: 978-0-387-94083-0Due: 23 December 1993

  • Softcover ISBN: 978-1-4612-7599-2Published: 15 September 2011

  • eBook ISBN: 978-1-4612-2596-6Published: 07 March 2013

  • Series ISSN: 0938-040X

  • Edition Number: 1

  • Number of Pages: XX, 587

  • Topics: Cell Biology, Human Physiology, Biochemistry, general

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