Analysis and Assessment of Cardiovascular Function

1. Front Matter

   Pages i-xvi

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2. Cardiovascular Function

   1. Front Matter

      Pages 1-1

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   2. Cardiovascular Concepts in Antiquity

      • Abraham Noordergraaf

      Pages 3-12

   3. A New Approach to the Analysis of Cardiovascular Function: Allometry

      • John K-J. Li

      Pages 13-29

3. Cardiac Muscle

   1. Front Matter

      Pages 31-31

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   2. Muscle Contraction Mechanics from Ultrastructural Dynamics

      • Joseph L. Palladino, Abraham Noordergraaf

      Pages 33-57

   3. Crossbridge Cycling and Cooperative Recruitment Can Account for Oscillatory Dynamics of Constantly Activated Heart

      • Kenneth B. Campbell, Robert D. Kirkpatrick

      Pages 58-69

   4. Modeling Reversible Mechanical Dysfunction in the Stunned Myocardium

      • Jia-Jung Wang, Gary M. Drzewiecki

      Pages 70-91

   5. Computer-Based Myocardial Tissue Characterization Using Quantitative Description of Texture

      • Aleksandra Mojsilović, Aleksandar N. Nešković, Miodrag Popović, Aleksandar D. Popović

      Pages 92-106

4. Coronary Circulation

   1. Front Matter

      Pages 107-107

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   2. Interpretation of Coronary Vascular Perfusion

      • H. Frederick Frasch, J. Yasha Kresh, Abraham Noordergraaf

      Pages 109-127

   3. New-Age Rapid Diagnosis of Acute Myocardial Injury

      • Sina Y. Rabbany

      Pages 128-141

5. Ventricular Dynamics

   1. Front Matter

      Pages 143-143

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   2. Modeling of the Effects of Aortic Valve Stenosis and Arterial System Afterload on Left Ventricular Hypertrophy

      • John K-J. Li, Ying Zhu, Michele Nanna

      Pages 145-155

   3. Ventricular Shape: Spherical or Cylindrical?

      • Susara C. J. E. Juznic, Gojmir Juznic, Bojan Knap

      Pages 156-171

   4. Pathophysiology of Diastole and Left Ventricular Filling in Humans: Noninvasive Evaluation

      • Cesare U. Rusconi, Giuseppe L. Ghizzoni, Tony Sabatini, Carlo A. Oneglia, Pompilio M. Faggiano

      Pages 172-192

   5. Echocardiographic Evaluation of Thrombolytic Intervention After Acute Myocardial Infarction

      • Aleksandar D. Popović

      Pages 193-200

6. Arterial/Ventricular Circulation

   1. Front Matter

      Pages 201-201

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   2. Modeling of Noninvasive Arterial Blood Pressure Methods

      • Gary M. Drzewiecki

      Pages 203-221

   3. Measurement and Applications of Arterial and Ventricular Pressure-Dimension Relationships in Animals and Humans

      • Jan Baan

      Pages 222-235

The objective of this book is to provide the researcher and clinician with the recent developments in the analysis and assessment of cardiovascular func­ tion. The chapters are organized into sections that correspond with the various anatomical levels of the cardiovascular system. To a large extent, recent focus on the cardiovascular system function has been directed at the molecular level to the near exclusion of the tissue and organ function. While this may be useful in developing new therapeutic drugs, it does not aid the cardiologist or surgeon, who routinely deal with patient symptoms. This book integrates the micro-level and organ-level function so that new infor­ mation may be assimilated into the cardiovascular system as a whole. Within each section, the chapters have been arranged to progress from recent theoretical developments, to experimental research, and finally to clinical applications. This approach facilitates the timely transfer of infor­ mation from basic research to the clinic. The strength of the analytical approach will be evident to the reader. The theoretical analysis offers guidance to experimental design and, in some cases, offers solutions where measurements are as yet unattainable. In moving from newly attained knowledge to clinical practice, this book emphasizes the noninvasive meth­ in the future as technological advances ods. Such methods are desirable occur and the trend towards early preventive diagnosis is sought. What follows are highlights of new developments covered in each section of the book.

• Monitor
• biomedical engineering
• blood pressure
• blood vessel
• cardiovascular
• cardiovascular function
• cardiovascular system
• circulation
• diagnosis
• electrophysiology
• heart
• heart rate
• pathophysiology
• physiology
• tissue

• Department of Biomedical Engineering, Rutgers University, Piscataway, USA

  Gary M. Drzewiecki, John K-J. Li

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