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Liver Pathology and Alcohol

Drug & Alcohol Abuse Reviews

  • Book
  • © 1991

Overview

Editors:
  1. Ronald R. Watson

    1. University of Arizona, Tucson, USA

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Part of the book series: Drug and Alcohol Abuse Reviews (DAAR, volume 2)

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Table of contents (23 chapters)

  1. Front Matter

    Pages i-xii
    Download chapter PDF

  2. Alcohol and Hepatic Iron Homeostasis

    • Barry J. Potter
    Pages 1-60

  3. The Pathogenesis of Inflammation in Alcoholic Liver Disease

    • F. Joseph Roll
    Pages 61-89

  4. Liver Cell Membrane Adaptation to Chronic Alcohol Consumption

    • Hagai Rottenberg
    Pages 91-115

  5. The Effect of Prenatal Alcohol Exposure on γ-Glutamyl Transpeptidase

    • Edward Reyes
    Pages 117-132

  6. Free Radicals and Alcohol Liver Injury

    • Lester A. Reinke, Paul B. McCay
    Pages 133-168

  7. Effects of Ethanol on Glutathione Metabolism

    • Mack C. Mitchell, David S. Raiford, Ariane Mallat
    Pages 169-194

  8. Liver Cancer

    • Siraj I. Mufti
    Pages 195-219

  9. Alcohol and Hepatic Protein Modification

    • Renee C. Lin, Lawrence Lumeng
    Pages 221-239

  10. Fatty Acid Ethyl Esters, Alcohol, and Liver Changes

    • Puran S. Bora, Louis G. Lange
    Pages 241-257

  11. Ethanol, Lipoprotein Metabolism, and Fatty Liver

    • M. R. Lakshman, Stuart J. Chirtel, Pradeep Ghosh
    Pages 259-285

  12. Effect of Ethanol on Splanchnic Blood Flow

    • Edward T. Knych
    Pages 287-307

  13. Interaction of Ethanol and the Glucocorticoids

    • Rolf F. Kletzien
    Pages 309-323

  14. Genetic and Dietary Control of Alcohol Degradation in Drosophila

    • Billy W. Geer, Robert R. Miller Jr., Pieter W. H. Heinstra
    Pages 325-373

  15. Human Liver Alcohol Dehydrogenase Gene Expression

    • Gregg Duester
    Pages 375-402

  16. Influence of Ethanol on Functional and Biochemical Characteristics of Skeletal Muscle

    • William E. Sonntag, Rhonda L. Boyd, Anselm D’Costa, Charles R. Breese
    Pages 403-423

  17. Alcohol and Liver Damage

    • Thomas M. Soranno, Lester G. Sultatos
    Pages 425-440

  18. Polymorphisms of Alcohol and Aldehyde Dehydrogenases and Their Significance for Alcohol Liver Diseases

    • Akira Yoshida, Akitaka Shibuya
    Pages 441-466

  19. Effects of Alcohol and Cocaine Abuse on the Antioxidant Systems, Nutritional Status, and Liver Damage

    • Olalekan E. Odeleye, Ronald R. Watson
    Pages 467-511

  20. Caffeine Metabolism

    • Charles P. Denaro, Neal L. Benowitz
    Pages 513-539
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Keywords

About this book

Alcohol and other drugs of abuse are major contributing factors to liver disease and its pathology. Alcoholic cirrhosis causes thousands of deaths each year in the United States, and encourages liver replacement. A better understanding of the mechanisms of liver pathology will significantly aid basic researchers and physicians in treating and preventing liver damage. This book is designed especially for those researchers wishing to understand alcoholic liver disease. Therefore the role of alcohol in changing nutrition and its nutritional effects on liver disease are reviewed. The generation of free radicals during alcohol use has been found to be an important cause of membrane changes, of cancer development, and of lipid alterations-and thus of liver pathology. In addition to alcohol, other drugs of abuse, including morphine, cocaine, marijuana, and caffeine have also been shown to be significant contributors to liver pathology. The prevalence of drug and alcohol use and abuse today means that liver disease will continue as a major social and medical problem. The explanation of its biological origins cannot fail to help us better understand and treat the disease in the years to come.

Reviews

...the techniques which have been used, the emphasis on free radicals and damage produced by them, are of general pathological interest and this book would certainly not be out of place in a pathology library.-Journal of Medical Microbiology

Editors and Affiliations

  • University of Arizona, Tucson, USA

    Ronald R. Watson

Bibliographic Information

  • Book Title: Liver Pathology and Alcohol

  • Book Subtitle: Drug & Alcohol Abuse Reviews

  • Editors: Ronald R. Watson

  • Series Title: Drug and Alcohol Abuse Reviews

  • DOI: https://doi.org/10.1007/978-1-4612-0421-3

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1991

  • Hardcover ISBN: 978-0-89603-206-4Published: 02 December 1991

  • Softcover ISBN: 978-1-4612-6755-3Published: 09 October 2012

  • eBook ISBN: 978-1-4612-0421-3Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XII, 620

  • Topics: Pathology

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