Connective Tissues in Arterial and Pulmonary Disease

1. Front Matter

   Pages i-xii

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2. Connective Tissues in Arterial Disease

   1. Front Matter

      Pages 1-1

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   2. Structure and Function of Aorta Proteoglycan

      • Theodore R Oegema Jr.

      Pages 5-56

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   3. Quantitation of Cells and Fibers in Histologic Sections of Arterial Walls: Advantages of Contour Tracing on a Digitizing Plate

      • Seymour Glagov, Joseph Grande, Draga Vesselinovitch, Christopher K. Zarins

      Pages 57-93

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   4. Biochemical Changes of the Arterial Wall in Atherosclerosis with Special Reference to Connective Tissue: Promising Experimental Avenues for their Prevention

      • Dieter M. Kramsch

      Pages 95-151

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   5. Biochemistry of Collagen with Special Reference to the Arterial Wall

      • R. Kent Rhodes

      Pages 153-171

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3. Connective Tissues in Pulmonary Disease

   1. Front Matter

      Pages 173-176

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   2. Connective Tissues and the Mechanical Behavior of Lungs

      • Gordon L. Snider

      Pages 177-216

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   3. Lathyrism and the Biochemistry of Elastin

      • Judith Ann Foster, Celeste B. Rich, Rogers M. Fred III

      Pages 217-246

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   4. Proteolytic Mechanisms and Pulmonary Emphysema

      • Gerard M. Turino, Stephen Keller, Tukaram V. Darnule, Mohamed M. Osman, Ines Mandl

      Pages 247-268

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   5. Histochemical Investigations of Elastin, Collastin, and Other Collagens

      • Holde Puchtler, Faye Sweat Waldrop, Susan N. Meloan

      Pages 269-331

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4. Holde Puchtler: An Appreciation

   1. Front Matter

      Pages 333-333

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   2. Proclamation

      • Thomas F. McDonald, A. Bleakley Chandler

      Pages 335-335

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   3. Greetings:

      • Holde Puchtler

      Pages 336-336

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   4. Essentials of Histological Staining: Dr. Holde Puchtler’s Contribution

      • Theodore H. Schiebler

      Pages 337-337

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5. Back Matter

   Pages 345-355

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The processes of distention and recoil have an essential role in the functions of arteries and lungs. In both organ systems, these processes involve to a great extent the connective tissues, in particular the manner in which the extracellular materials are arranged to afford such movements. This book concerns the microenvironment of the connective tissues in the walls of arteries and the stroma of lungs. Proteoglycans, collagen, and elastic fibers and their interrelationships are discussed by eight scientists who are established researchers in this area. Their reports include important findings on how this microenvironment is altered in diseases such as atherosclerosis, emphysema, and pulmonary fibrosis. The concepts developed result from studies at the biochemical, macromolecular, ultrastructural, and light microscopic levels. Taken col­ lectively, the reports focus attention upon the role of the connective tissues in arterial and lung distensibility and how alterations in the connective tissues result in the loss of this function. Medical researchers and physicians interested in arterial or lung functions or diseases will find the scientific approaches and findings of the authors innovative and provocative. Students of stereologic morphometry will be particularly interested in the quantitative studies of cells and fibers in arterial walls; histologists and pathologists will find the chapter on histochemical staining interesting from both a scientific and historic viewpoint.

• Arterien
• Arterienverkalkung
• Bindegewebe
• Lungenerkrankung
• Puchtler, Holde
• Stent
• Tissues
• atherosclerosis
• tissue

• School of Medicine, Medical College of Georgia, Augusta, USA

  Thomas F. McDonald

• Department of Pathology, School of Medicine, Medical College of Georgia, Augusta, USA

  A. Bleakley Chandler

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