Neural Membranes

1. Front Matter

   Pages i-xii

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2. Membrane Phospholipids

   1. Front Matter

      Pages 1-1

      PDF

   2. Phospholipid Metabolism in Neural Membranes

      • Giuseppe Porcellati

      Pages 3-35

   3. The Involvement of Lipids in Signal Transmission Across Cell Membranes of the Nervous System

      • George Hauser

      Pages 37-65

   4. Involvement of Phospholipid Metabolites in Neuronal Membrane Functions

      • Grace Y. Sun, Wilson Tang, M. Dorota Majewska, David W. Hallett, Laurie Foudin, Steven Huang

      Pages 67-95

   5. Effects of Catecholamines and their Metabolites and other Pharmacological Agents on Arachidonic Acid Metabolism and Prostaglandin Release by Rabbit Iris Muscle and Iris Microsomes

      • Ata A. Abdel-Latif, Jack P. Smith, Sardar Y. K. Yousufzai, Richard K. Dover

      Pages 97-122

   6. Free Arachidonic and Docosahexaenoic Acid Accumulation in the Central Nervous System During Stimulation

      • Nicolas G. Bazan, Susana G. Morelli de Liberti, Elena B. Rodriguez de Turco, Maria F. Pediconi

      Pages 123-140

   7. The Role of Arachidonic Acid in Cellular Brain Edema

      • Pak Hoo Chan, Robert A. Fishman, Susan Longar, Sylvia Chen, Susan Chew

      Pages 141-152

   8. Metabolism of Docosahexaenoic-Acid-Containing Species of Ether Phospholipid in Rat Brain

      • Yasuo Masuzawa, Yoshiaki Onuma, Keizo Waku, Yoshio Ishima

      Pages 153-170

   9. The Effect of Dietary Choline on Brain Phospholipid Content

      • Charles E. Pendley II, Lloyd A. Horrocks, Ronald F. Mervis

      Pages 171-190

   10. Solubilization, Purification and Properties of Membrane-Bound Brain Enzymes which Biosynthesize Phosphoinositides

       • Joseph Eichberg, J. Robert Bostwick, Abdallah Ghalayini

       Pages 191-213

3. Receptors

   1. Front Matter

      Pages 215-215

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   2. Demonstration of Gaba-Synthesizing Enzyme, Gad, Benzodiazepine Receptor and Coated Vesicles in the Vertebrate Nervous System

      • Jang-Yen Wu, Ching-Tarng Lin, Y. Y. T. Su

      Pages 217-239

   3. Roles of Synaptic Membranous Phospholipids in the Modulation of Cerebral GABA and Benzodiazepine Receptor Bindings

      • Kinya Kuriyama, Yukio Yoneda

      Pages 241-257

   4. Characterization and Isolation of Dopamine-Binding Proteins in Rat CNS by Gel Electrophoresis & Affinity Chromatography

      • Louise L. Hsu, Kayoko Moroi, Angelos E. Halaris

      Pages 259-274

   5. Effects of Ascorbate on Post-Synaptic Serotonin Binding Sites in Rat Brains

      • Jean Chen Shih, Samar F. Muakkassah-Kelly, Jeffrey W. Andresen, Paul Hochstein

      Pages 275-287

   6. Membrane Properties of Isolated Horizontal Cells in the Teleost Retina

      • Dominic Man-Kit Lam, George S. Ayoub

      Pages 289-313

4. Membrane Structure and Functions

   1. Front Matter

      Pages 315-315

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   2. The Kindling Effect of Ethanol on Neuronal Membranes

      • Albert Y. Sun

      Pages 317-340

   3. Response of Brain Cell Culture to Ethanol: Morphological and Biochemical Studies

      • T. C. Jou, A. Y. Sun

      Pages 341-354

One of the most active and productive areas of biological science in the past decade has been the study of the biochemical and biophysical prop­ erties of cell membranes. There is little doubt that membranes are essen­ tial components of all cellular systems and that each type of membrane manifests specific and characteristic cellular functions. In the nervous system, important events such as neurotransmission, receptor binding, ion transport, axonal transport, and cell uptake are all known to take place within the neural cell membrane. Phospholipids, one of the major components of membranes, not only provide the membrane with its structural integrity and physical proper­ ties, but also play an important role in regulating membrane function. Attention has recently been focused on the asymmetric localization of these molecules, the identification of discrete metabolic pools of phospholipids within the membrane matrix, and their involvement in sig­ nal transmission. Although synaptic membranes generally lack an active mechanism for the de novo biosynthesis of phospholipids, a number of enzymic routes are present for their interconversions and for facilitating metabolic turnover. Metabolites generated during the interconversion reactions may also exert a great influence in modulating membrane func­ tions. The phosphogylcerides of neural membranes are especially enriched in polyunsaturated fatty acids. However, only very small amounts of these fatty acids are present in the free form, and they are maintained in dynamic equilibrium with the membrane phospholipids.

• Nervous System
• attention
• brain
• brain edema
• catecholamines
• central nervous system
• dopamine
• membrane
• muscle
• proteins
• receptor

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