The Menopause

1. Front Matter

   Pages i-xiv

   PDF

2. Origin of Estrogen and Regulation of Its Formation in Postmenopausal Women

   • M. Linette Casey, Paul C. MacDonald

   Pages 1-8

3. End Organ Response to Estrogen Deprivation

   • Richard L. Voet

   Pages 9-22

4. The Climacteric

   • Clare D. Edman

   Pages 23-33

5. Postmenopausal Osteoporosis

   • Charles Y. C. Pak

   Pages 35-54

6. Biologic Effects of Natural and Synthetic Estrogens

   • J. Gerald Quirk Jr., George D. Wendel Jr.

   Pages 55-75

7. Estrogen Replacement Therapy

   • Clare D. Edman

   Pages 77-84

8. The Role of Progestational Agents in Hormone Replacement Therapy

   • Marc A. Fritz, Leon Speroff

   Pages 85-102

9. Adenocarcinoma of the Endometrium

   • Samuel Lifshitz, Steven G. Bernstein

   Pages 103-129

10. Urinary Tract Disorders

    • Robert C. Corlett

    Pages 131-138

11. Surgery in the Postmenopausal Woman

    • Félix Krauer

    Pages 139-150

12. Psychobiologic Aspects of the Menopausal Syndrome

    • Meir Steiner

    Pages 151-160

13. Menopause and Sleep

    • Veronica A. Ravnikar, Isaac Schiff, Quentin R. Regestein

    Pages 161-171

14. Sexuality

    • James P. Semmens

    Pages 173-180

15. The Breast

    • Douglas J. Marchant

    Pages 181-198

16. Sports and Exercise

    • Mona M. Shangold

    Pages 199-203

17. The Perimenopausal Woman in Literature

    • Marie DuMont Low

    Pages 205-213

18. Back Matter

    Pages 215-225

    PDF

Nearly one-half of an American woman's life is spent after the cessation of reproductive function. A woman of 40 years has an additional life expectancy of nearly 40 years; a woman of 75, over 11 years. This pattern of longevity is likely to continue, so that by the year 2000, it has been estimated, 30 percent of the female population will be postmenopausal. While it is difficult to separate the results of aging from those of estrogen deprivation, it is important that we try to do so, since the results of the latter are amenable to treatment. The medical infirmities resulting from estrogen deprivation take a high toll among postmenopausal women. Nearly 200,000 hip fractures occur annually in this group, resulting in 15,000 deaths and a high morbidity rate. Sleep disorders, compromised sexuality, psychomotor alterations of the climacterium, and urinary tract disorders all contribute to a lowered quality of life. Appropriate treatment of these disturbing postmenopausal conditions requires an understanding of the underlying bio­ chemical, endocrinologic, psychologic, and pathophysiologic al­ terations of estrogen deprivation. Toward this end, the reader will find herein chapters dealing with estrogen metabolism in the postmenopausal female, end-organ response to estrogen deprivation, and bone metabolism and osteoporosis. Next, the reader will find chapters dealing with specific or­ gans, organ systems, or conditions related to the quality of life; for example, sexuality, urinary tract problems, sleep disorders, the breast, sports and exercise, the climacteric, and the psycho­ biology of the menopause.

• Endometrium
• biology
• hormones
• menopause
• regulation

• Division of Gynecologic Oncology, University of Texas Health Science Center at Dallas, USA

  Herbert J. Buchsbaum

Policies and ethics