Skip to main content
SpringerLink
Log in
Birkhäuser

Myofibrillogenesis

  • Book
  • © 2002

Overview

Editors:
  1. Dipak K. Dube

    1. Department of Medicine and Department of Cell and Developmental Biology, SUNY Upstate Medical University, Syracuse, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Cardiovascular Molecular Morphogenesis (CARDMM)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (14 chapters)

  1. Front Matter

    Pages i-xvi
    Download chapter PDF

  2. Assembly of Myofibrillar Proteins in Striated Muscle

    1. Front Matter

      Pages 1-1
      Download chapter PDF

    2. Myofibrillogenesis in Cardiac Muscle

      • Joseph W. Sanger, Jean M. Sanger
      Pages 3-20

    3. Dynamics of Contractile Proteins Constituting Myofibrils in Living Muscle Cells

      • Yutaka Shimada, Tin Moe Nwe, Fukuko Hasebe-Kishi, Homare Suzuki
      Pages 21-39

    4. Emergence of the First Myofibrils and Targeting Mechanisms Directing Sarcomere Assembly in Developing Cardiomyocytes

      • Elisabeth Ehler, Jean-Claude Perriard
      Pages 41-58

    5. Tropomodulin: An Important Player in Cardiac Myofibrillogenesis

      • Catherine McLellan, Carol C. Gregorio
      Pages 59-69

  3. Maintenance and Manipulation of Myofibrillar Organization

    1. Front Matter

      Pages 71-71
      Download chapter PDF

    2. Maintaining the Fully Differentiated Cardiac Sarcomere

      • Daniel E. Michele, Joseph M. Metzger
      Pages 73-85

    3. Manipulation of Myofibrillogenesis in Whole Hearts

      • Robert W. Zajdel, Matthew D. McLean, Christopher R. Denz, Syamalima Dube, Larry F. Lemanski, Dipak K. Dube
      Pages 87-100

  4. Regulation of Expression of Myofibrillar Proteins

    1. Front Matter

      Pages 101-101
      Download chapter PDF

    2. Molecular Regulation of Cardiac Myofibrillogenesis: Roles of Serum Response Factor, Nkx2-5, and GATA-4

      • Robert J. Schwartz, Jorge Sepulveda, Narasimhaswamy S. Belaguli
      Pages 103-127

    3. Regulation and Organization of Human Troponin Genes

      • Paul J. R. Barton, Kimberley A. Dellow, Pankaj K. Bhavsar, Martin E. Cullen, Antony J. Mullen, Nigel J. Brand
      Pages 129-141

    4. Signal Transduction in Myofibrillogenesis, Cell Growth, and Hypertrophy

      • M. A. Q. Siddiqui, Michael Wagner, Eduardo Mascareno, Saiyid Shafiq
      Pages 143-152

    5. Cytoskeletal Gene Expression in the Developing Cardiac Conduction System

      • Robert E. Welikson, Takashi Mikawa
      Pages 153-177

  5. Heart Development and Myofibrillar Organization

    1. Front Matter

      Pages 179-179
      Download chapter PDF

    2. Onset of a Cardiac Phenotype in the Early Embryo

      • Leonard M. Eisenberg, Carol A. Eisenberg
      Pages 181-205

    3. Cellular, Molecular, and Developmental Studies on Heart Development in Normal and Cardiac Mutant Axolotls, Ambystoma mexicanum

      • Larry F. Lemanski, Xupei Huang, R. W. Zajdel, Sharon L. Lemanski, Chi Zhang, Fanyin Meng et al.
      Pages 207-222

  6. Cardiomyopathy and Myofibrillar Organization

    1. Front Matter

      Pages 223-223
      Download chapter PDF

    2. The Function of Normal and Familial Hypertrophic Cardiomyopathy-Associated Tropomyosin

      • Rethinasamy Prabhakar, Kathy Pieples, Ganapathy Jagatheesan, Stephanie Burge, David F. Wieczorek
      Pages 225-235

    3. Cardiomyopathies and Myofibril Abnormalities

      • Jeffrey A. Towbin, Neil E. Bowles
      Pages 237-263
Back to top

Keywords

About this book

Myofibrillogenesis has been studied extensively over the last 100 years. Until recently, we have not had a comprehensive understanding of this fundamental process. The emergence of new technologies in molecular and cellular biology, combined with classical embryology, have started to unravel some of the complexities of myofibril assembly in striated muscles. In striated muscles, the contractile proteins are arranged in a highly ordered three dimensional lattice known as the sarcomere. The assembly of a myofibril involves the precise ordering of several proteins into a linear array of sarcomeres. Multiple isoforms in many of these proteins further complicate the process, making it difficult to define the precise role of each component. This volume has been compiled as a comprehensive reference on myofibrillogenesis. In addition, the book includes reviews on myofibrillar disarray under various pathological conditions, such as familial hypertrophic cardiomyopathy (FHC), and incorporates a section on the conduction system in the heart. Much of the information in this volume has not been described elsewhere. Presented in a manner to be of value to students and teachers alike, "Myofibrillogenesis" will be an invaluable reference source for all in the fields of muscle biology and heart development.

Editors and Affiliations

  • Department of Medicine and Department of Cell and Developmental Biology, SUNY Upstate Medical University, Syracuse, USA

    Dipak K. Dube

Bibliographic Information

  • Book Title: Myofibrillogenesis

  • Editors: Dipak K. Dube

  • Series Title: Cardiovascular Molecular Morphogenesis

  • DOI: https://doi.org/10.1007/978-1-4612-0199-1

  • Publisher: Birkhäuser Boston, MA

  • eBook Packages: Springer Book Archive

  • Copyright Information: Birkhäuser Boston 2002

  • Hardcover ISBN: 978-0-8176-4226-6Published: 19 October 2001

  • Softcover ISBN: 978-1-4612-6658-7Published: 21 October 2012

  • eBook ISBN: 978-1-4612-0199-1Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XVI, 270

  • Topics: Animal Anatomy / Morphology / Histology, Cell Biology

Publish with us

Policies and ethics

Back to top

Search

Navigation