Overview
- Provides a timely overview of the nascent field of anticancer genes, a novel concept in cancer research, emphasising their unique features and advantages
- Describes the achievements and challenges of the clinical application of anticancer genes
- Considers the opportunities to identify additional genes, and mechanisms to introduce these genes into tumor cells for therapeutic benefit
- Includes supplementary material: sn.pub/extras
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 818)
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Table of contents (13 chapters)
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Front Matter
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Cellular Anticancer Genes
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Front Matter
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Anticancer Gene Therapy
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Front Matter
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Back Matter
Keywords
About this book
This book discusses the emergence of a new class of genes with a specific anticancer activity. These genes, recently defined as “Anticancer Genes”, are reviewed in individual chapters on their mode of action, the specific cell death signals they induce, and the status of attempts to translate them into clinical application.
Anticancer Genes provides an overview of this nascent field, its genesis, current state, and prospect. It discusses how Anticancer Genes might lead to the identification of a repertoire of signaling pathways directed against cellular alterations that are specific for tumor cells.
With contributions from experts worldwide, Anticancer Genes is an essential guide to this dynamic topic for researchers and students in cancer research, molecular medicine, pharmacology and toxicology and genetics as well as clinicians and clinical researchers interested in the therapeutic potential of this exciting new field.
Editors and Affiliations
Bibliographic Information
Book Title: Anticancer Genes
Editors: Stefan Grimm
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-1-4471-6458-6
Publisher: Springer London
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag London Ltd., part of Springer Nature 2014
Hardcover ISBN: 978-1-4471-6457-9Published: 28 July 2014
Softcover ISBN: 978-1-4471-7257-4Published: 03 September 2016
eBook ISBN: 978-1-4471-6458-6Published: 08 July 2014
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: XII, 283
Number of Illustrations: 9 b/w illustrations, 31 illustrations in colour
Topics: Molecular Medicine, Cancer Research, Gene Therapy, Human Genetics, Pharmacology/Toxicology