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  • Book
  • © 1997

Neuromuscular Diseases

A Practical Approach to Diagnosis and Management

Authors:

  1. Michael Swash

    1. St. Bartholomew’s and The Royal London Hospital School of Medicine and Dentistry at Queen Mary Westfield College, and The Royal London Hospital, London, UK

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    You can also search for this author in PubMed   Google Scholar

  2. Martin S. Schwartz

    1. Atkinson Morley’s Hospital, London, UK
      St George’s Hospital, London, UK

    View author publications

    You can also search for this author in PubMed   Google Scholar

  • theoretical information that will be useful to managing patients with neuromuscular problems.

  • Both authors are recognised experts in the field of neuromuscular disorders and the book is based on their extensive and continuing clinical and research experience.

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Table of contents (21 chapters)

  1. Front Matter

    Pages i-xviii
    PDF

  2. Clinical Assessment and Measurement

    • Michael Swash, Martin S. Schwartz
    Pages 1-17

  4. Muscle and Nerve Biopsies

    • Michael Swash, Martin S. Schwartz
    Pages 43-68

  5. Pathophysiological Correlations and Compensatory Mechanisms

    • Michael Swash, Martin S. Schwartz
    Pages 69-84

  6. Classification of Neuromuscular Diseases

    • Michael Swash, Martin S. Schwartz
    Pages 85-87

  7. Diseases of Anterior Horn Cells

    • Michael Swash, Martin S. Schwartz
    Pages 89-120

  8. A Clinical Approach to the Neuropathies

    • Michael Swash, Martin S. Schwartz
    Pages 121-132

  9. Nerve Entrapment and Compression Syndromes and Other Mononeuropathies

    • Michael Swash, Martin S. Schwartz
    Pages 133-160

  10. Nerve Root and Plexus Lesions

    • Michael Swash, Martin S. Schwartz
    Pages 161-172

  11. Genetically Determined Neuropathies

    • Michael Swash, Martin S. Schwartz
    Pages 173-200

  12. Acquired Polyneuropathies

    • Michael Swash, Martin S. Schwartz
    Pages 201-255

  13. Myasthenia Gravis and Other Myasthenic Syndromes

    • Michael Swash, Martin S. Schwartz
    Pages 257-283

  14. Inflammatory Myopathies and Related Disorders

    • Michael Swash, Martin S. Schwartz
    Pages 285-306

  15. Muscular Dystrophies

    • Michael Swash, Martin S. Schwartz
    Pages 307-341

  16. Myotonic Syndromes

    • Michael Swash, Martin S. Schwartz
    Pages 343-362

  17. Childhood Myopathies

    • Michael Swash, Martin S. Schwartz
    Pages 363-375

  18. Inherited Metabolic Myopathies

    • Michael Swash, Martin S. Schwartz
    Pages 377-413

  19. Endocrine Myopathies

    • Michael Swash, Martin S. Schwartz
    Pages 415-424

  20. Drug-Induced Toxic and Nutritional Myopathies

    • Michael Swash, Martin S. Schwartz
    Pages 425-432
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About this book

Nine years have elapsed since the second edition of this book was published. In this time the principal advances in neuromuscular diseases have been in the application of molecular genetics to understanding the aetiology and pathogenesis of this group of disorders. As a result many previously unrecognised disorders have been charac­ terised. Some clinical syndromes, such as the limb girdle dystrophies, have become better defined. In many such instances the new genetic information has led to major advances in knowledge of the biology of cell structures, for example, the membrane structural and channel proteins. The clinical syndromes themselves, and their patho­ logical and electrophysiological characteristics, however, remain as important as ever, since they constitute the clinical problem itself and, indeed, the database from which all other concepts emerge. Knowledge of the pathogenesis, genetics, and molecular biology of neuromuscular disorders is essential both in developing and applying new therapies and preventive measures, and in formulating genetic and prognostic advice. However, this informa­ tion does not necessarily always define clinically useful syndromes. Myotonia, for example, is an electrophysiological finding in some syndromes in which it is un­ detectable by clinical examination, although the phenomenon itself was originally defined as a clinical entity. The limb girdle muscular dystrophy syndromes can be defined by severity, distribution of weakness, age of onset, sex distribution and other characteristics and many of these can be better understood by study of the under­ lying defect in cell structural proteins.
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Keywords

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Authors and Affiliations

  • St. Bartholomew’s and The Royal London Hospital School of Medicine and Dentistry at Queen Mary Westfield College, and The Royal London Hospital, London, UK

    Michael Swash

  • Atkinson Morley’s Hospital, London, UK

    Martin S. Schwartz

  • St George’s Hospital, London, UK

    Martin S. Schwartz

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Bibliographic Information

  • Book Title: Neuromuscular Diseases

  • Book Subtitle: A Practical Approach to Diagnosis and Management

  • Authors: Michael Swash, Martin S. Schwartz

  • DOI: https://doi.org/10.1007/978-1-4471-3834-1

  • Publisher: Springer London

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag London 1997

  • Softcover ISBN: 978-1-4471-3836-5Published: 05 January 2013

  • eBook ISBN: 978-1-4471-3834-1Published: 14 March 2013

  • Edition Number: 3

  • Number of Pages: XVIII, 541

  • Number of Illustrations: 331 b/w illustrations

  • Additional Information: Jointly published with YEE LEE Book Co., Ltd.

  • Topics: Neurology, Rheumatology, Pathology

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Buy it now

eBook USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

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