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Implantation

Biological and Clinical Aspects

  • Book
  • © 1988

Overview

Editors:
  1. Michael G. Chapman

    1. Department of Obstetrics and Gynaecology, Guy’s Hospital, London, UK

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  2. J. Gedis Grudzinskas

    1. Academic Unit of Obstetrics and Gynaecology, The London Hospital, Whitechapel, London, UK

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  3. Tim Chard

    1. Academic Unit of Reproductive Physiology, St Bartholomew’s Hospital Medical College, London, UK

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Table of contents (18 chapters)

  1. Front Matter

    Pages i-xii
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  2. General

    1. Front Matter

      Pages 1-1
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    2. Embryo Implantation in Primates

      • J. P. Hearn, G. E. Webley, A. A. Gidley-Baird
      Pages 3-13

  3. Pituitary and Ovarian Hormones

    1. Front Matter

      Pages 15-15
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    2. Pituitary and Ovarian Hormones in Implantation and Early Pregnancy

      • E. A. Lenton
      Pages 17-29

  5. Endometrial/Decidual Proteins

    1. Front Matter

      Pages 93-93
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    2. Synthesis and Secretion of Proteins by the Endometrium and Decidua

      • S. C. Bell
      Pages 95-118

    3. Characterisation, Biological Action and Clinical Studies of Endometrial Proteins

      • M.-L. Huhtala, M. Seppälä, M. Julkunen, R. Koistinen
      Pages 119-134

    4. Biological Activity of Placental Protein 14

      • A. E. Bolton, A. G. Pockley, E. A. Mowles, R. J. Stoker, O. M. R. Westwood, M. G. Chapman
      Pages 135-144

  6. Prostaglandins in Reproduction

    1. Front Matter

      Pages 145-145
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    2. Prostaglandins and the Establishment of Pregnancy

      • S. K. Smith, R. W. Kelly
      Pages 147-160

  7. Reproductive Immunology

    1. Front Matter

      Pages 161-161
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    2. Current Concepts of Immunoregulation of Implantation

      • D. A. Clark
      Pages 163-175

    3. The Complement System in Normal Pregnancy

      • B. Teisner, D. Tornehave, J. Hau, J. G. Westergaard, H. K. Poulsen
      Pages 177-182

    4. Spontaneous and Recurrent Abortion: Epidemiological and Immunological Considerations

      • L. Regan
      Pages 183-195
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Keywords

About this book

The advent of assisted conception procedures such as in-vitro fertili­ sation (IVF) has provided the impetus for exploration of the factors that lead to the establishment of pregnancy. This collection of papers from leading research workers brings together current concepts of the processes which may be of importance in implantation. The complex signals from the embryo to the ovary, endometrium and myometrium are now being revealed through studies in both primates and other mammalian species. This book addresses the interrelationship of pituitary and ovarian hormones in controlling ovulation and the preparation of the intrauterine environment for implantation. Once fertilisation has occurred and trophoblast has formed, the next vital step is the production of materials which signal the presence of the pregnancy to the rest of the body. Trophoblastic proteins and other early-pregnancy factors are prime candidates for this role. Recent studies have emphasised the importance of the intrauterine environment in implantation. Specific secretory products of the endometrium have great potential in this process. The prostaglandins also play an essential part. Immunological adjustments are now considered a condition for the successful establishment of pregnancy. The possible use of immuno­ therapy in the treatment of recurrent abortion has highlighted interest in this area. The use of immunological techniques for contraception are in their infancy but offer much hope for the future.

Editors and Affiliations

  • Department of Obstetrics and Gynaecology, Guy’s Hospital, London, UK

    Michael G. Chapman

  • Academic Unit of Obstetrics and Gynaecology, The London Hospital, Whitechapel, London, UK

    J. Gedis Grudzinskas

  • Academic Unit of Reproductive Physiology, St Bartholomew’s Hospital Medical College, London, UK

    Tim Chard

Bibliographic Information

  • Book Title: Implantation

  • Book Subtitle: Biological and Clinical Aspects

  • Editors: Michael G. Chapman, J. Gedis Grudzinskas, Tim Chard

  • DOI: https://doi.org/10.1007/978-1-4471-3529-6

  • Publisher: Springer London

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1988

  • Softcover ISBN: 978-1-4471-3531-9Published: 08 December 2012

  • eBook ISBN: 978-1-4471-3529-6Published: 14 March 2013

  • Edition Number: 1

  • Number of Pages: XII, 258

  • Number of Illustrations: 33 b/w illustrations

  • Topics: Obstetrics/Perinatology/Midwifery, Cell Biology, Biochemistry, general

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