Clinical In Vitro Fertilization

1. Front Matter

   Pages i-xii

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2. History

   • Ann Westmore

   Pages 1-10

3. Current Status and Future Prospects

   • Carl Wood, Gordon Baker, Alan Trounson

   Pages 11-26

4. Selection of Patients

   • Carl Wood, Ian Johnston

   Pages 27-36

5. Patient Management and Preparation for In Vitro Fertilization

   • Gabor Kovacs

   Pages 37-47

6. Patient Management—Treatment Cycle

   • John C. McBain, Alan Trounson

   Pages 49-65

7. Oocyte Pick-up

   • Bruce Downing

   Pages 67-81

8. Assessment and Preparation of Semen for In Vitro Fertilization

   • Maha Mahadevan, Gordon Baker

   Pages 83-97

9. In Vitro Fertilization and Embryo Growth

   • Linda Mohr, Alan Trounson

   Pages 99-115

10. Embryo Transfer

    • John Leeton, John Kerin

    Pages 117-136

11. Biological Risks of In Vitro Fertilization and Embryo Transfer

    • Ian L. Pike

    Pages 137-146

12. Pregnancy Care

    • William A. W. Walters, Peter M. Renou

    Pages 147-156

13. Summary of Results

    • Andrew Speirs, Alan Trounson, Graham M. Warnes, John L. Yovich, Douglas M. Saunders, Chris Chen

    Pages 157-163

14. The Establishment of an In Vitro Fertilization Programme

    • John Kerin, Carl Wood, Gabor Kovacs

    Pages 165-175

15. Ethics

    • Carl Wood, John Kerin

    Pages 177-188

16. Back Matter

    Pages 189-212

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Man is entering a new era as a result of advances in human reproduction. Techniques have been developed to assist in the creation of man-artificial insemination and, now, in vitro fertilization (IVF). Soon, other new methods, based upon current advances of the IVF procedure, will develop to improve the quality of human reproduction. The book describes the conceptual framework and details of technique concerned with in vitro fertilization and embryo transfer (ET). Edwards and Steptoe first described the technique of IVF and ET and the subsequent births of two normal babies. Since then, the success rate of the system has been improved by the use of fertility drugs to provide more oocytes and preincubation to mature the oocyte before fertilization. As a result of the continued research from Melbourne and Cambridge, more than 100 babies have been born. A free interchange of information between the Cambridge and Melbourne groups has led to a predictable success rate of 15%-20% per laparoscopy, and infertility centres all over the world are now copying the techniques. It is an appropriate time to inform doctors and scientists to help them understand the various procedures involved in IVF and ET. While many advances will occur in the future, the establishment of high success rates in several of the critical steps in the procedure-oocyte pick-up rate (90%), fertilization (>90%) and early embryo development (70%-90% )-signifies that some of the new techniques are stabilized sufficiently to warrant transmission of information by text, rather than scientific journal.

• Wood
• birth
• embryo
• fertility
• in vitro fertilization
• infertility
• künstliche Befruchtung
• reproduction

• Department of Obstetrics and Gynaecology, Monash University, Queen Victoria Medical Centre, Melbourne, Australia

  Carl Wood

• Queen Victoria Medical Centre, Melbourne, Australia

  Alan Trounson

Policies and ethics