Clinical Aspects of Blood Viscosity and Cell Deformability

1. Front Matter

   Pages i-xvi

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2. Blood Cell Deformability

   1. Front Matter

      Pages 1-1

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   2. Problems of Measurement of Red Cell Deformability

      • H. Kiesewetter, H. Schmid-Schönbein, D. Seiffge, P. Teitel

      Pages 3-7

   3. Erythrocyte Flexibility and Whole-blood Viscosity

      • J. A. Sirs

      Pages 9-18

   4. New Methods for Red Cell Deformability Measurement

      • H. Kiesewetter, K. Mussler, P. Teitel, U. Dauer, H. Schmid-Schönbein, R. Spohr

      Pages 19-26

   5. Measurement and Influence of White Cell Deformability

      • U. Bagge, P.-I. Brånemark, R. Skalak

      Pages 27-36

   6. The Measurement of Red Blood Cell Deformability

      • J. C. Barbenel

      Pages 37-45

3. General Aspects of Blood Rheology

   1. Front Matter

      Pages 47-47

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   2. Interaction of Vasomotion and Blood Rheology in Haemodynamics

      • H. Schmid-Schönbein

      Pages 49-66

   3. Measurement of Whole-blood Viscosity

      • J. A. Dormandy

      Pages 67-78

   4. Measurement of Plasma Viscosity

      • J. Harkness

      Pages 79-87

4. Blood Rheology, Blood Flow and Vascular Occlusion

   1. Front Matter

      Pages 89-89

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   2. Relationship of Blood Rheology to Blood Flow

      • D. Charlesworth

      Pages 91-96

   3. Haematocrit, Blood Viscosity, Cerebral Blood Flow, and Vascular Occlusion

      • T. C. Pearson, P. R. D. Humphrey, D. J. Thomas, G. Wetherley-Mein

      Pages 97-107

   4. Sickle-cell Disease and Vascular Occlusion

      • J. Stuart, M. W. Kenny

      Pages 109-122

   5. Circulatory Complications of Leukaemia and Paraproteinaemia

      • F. E. Preston

      Pages 123-132

   6. Occlusive Arterial Disease and Blood Rheology

      • G. D. O. Lowe, M. M. Drummond, C. D. Forbes, J. C. Barbenel

      Pages 133-148

5. Blood Rheology in Medicine and Surgery

   1. Front Matter

      Pages 149-149

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   2. Blood Viscosity in Diabetes Mellitus

      • A. J. Barnes

      Pages 151-162

   3. Surgery and Post-operative Thrombosis

      • P. N. Matthews

      Pages 163-174

After many years of relative neglect, the importance of study of factors governing blood flow has at last achieved recognition; in this volume are documented many of the techniques, and the basic scientific and clinical observations, which have helped to open up understanding of this highly important aspect of human physiology and pathology in recent years. The text is logically divided into five sections beginning with blood cell deformability, then moving on to theoretical consideration of blood rheology, followed by accounts of the interrelationships between rheology, blood flow and vascular occlusion. The final two sections deal with blood rheology in clinical practice and therapeutic aspects of the study of blood flow. As regards blood cell deformability (Section A), the basic problem is set out by Kiesewetter and colleagues in the first paragraph of chapter 1 (p. 3), in which they point out that whereas human erythrocytes at rest have a diameter of approxi­ mately 7. 5 /-tm, nutritive capillaries have diameters ranging from 3-5 /-tm, and chapters in section A give an account of the ways in which the red cell can undergo deformation to permit capillary perfusion and the maintenance of the microcirculation.

• Blutviskosität
• Zellerkrankung
• blood
• cell
• physiology

• University Department of Medicine, Royal Infirmary, Glasgow, Scotland

  G. D. O. Lowe, C. D. Forbes

• Bioengineering Unit, University of Strathclyde, Glasgow, Scotland

  J. C. Barbenel

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