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Cellular and Molecular Biology of Atherosclerosis

  • Book
  • © 1992

Overview

Editors:
  1. Antonio M. Gotto

    1. The Methodist Hospital and Baylor College of Medicine, Houston, USA

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Part of the book series: Argenteuil Symposia (ARGENTEUIL)

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-xv
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  2. Morphological Findings in the Coronary Arteries in Fatal Coronary Artery Disease

    • W. C. Roberts
    Pages 1-20

  3. The L-Arginine: Nitric Oxide Pathway in Physiology and Pathology

    • S. Moncada, E. A. Higgs
    Pages 21-35

  4. Endothelial Activation: Its Role in Inflammation, Vascular Injury and Atherogenesis

    • R. S. Cotran
    Pages 37-44

  5. Basic Fibroblast Growth Factor in Vascular Development and Atherogenesis

    • W. Casscells
    Pages 45-59

  6. The Monocyte and Endothelial Injury in Atherogenesis

    • R. G. Gerrity
    Pages 61-69

  7. Lp [a]: A Lipoprotein Class with Atherothrombotic Potential

    • A. M. Scanu
    Pages 71-76

  8. Modified Lipoproteins and Atherogenesis

    • J. A. Berliner, M. Territo, A. Amdalibi, M. Navab, F. Liao, S. Cushing et al.
    Pages 77-81

  9. The Molecular Biology of Apolipoprotein B

    • J. Scott
    Pages 83-92

  10. Structure and Evolution of the Apolipoprotein and Lipase Gene Families

    • L. Chan, W. Hide, Yau-Wen Yang, Wen-Hsiung Li
    Pages 93-107

  11. A Gln to Arg Substitution in the Adducin Family of Proteins is a Necessary but not Sufficient Factor for High Blood Pressure in Rats of the Milan Hypertensive Strain

    • F. E. Baralle
    Pages 109-119

  12. Genetic Control of Plasma Lipid, Lipoprotein and Apolipoprotein Levels: From Restriction Fragment Length Polymorphisms to Specific Mutations

    • S. Humphries, A. Dunning, Chun-Fang Xu, P. Talmud
    Pages 121-133

  13. Receptor Regulation of Lipoprotein Metabolism

    • U. Beisiegel
    Pages 135-143

  14. The High-Density Lipoprotein Receptor

    • J. F. Oram
    Pages 145-152

  15. High-Density Lipoprotein Cholesterol, Triglycerides and Coronary Heart Disease

    • J. R. Patsch, G. Miesenboeck
    Pages 153-157

  16. Apolipoproteins, Reverse Cholesterol Transport and Coronary Heart Disease

    • G. Assmann, A. von Eckardstein, H. Funke
    Pages 159-166

  17. Cholesterol-Lowering Clinical Trials: Where Do We Go From Here?

    • A. M. Gotto Jr
    Pages 167-176

  18. Back Matter

    Pages 177-180
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Keywords

About this book

Atherosclerotic cardiovascular disease remains the major cause of death and disability in Western society. The field of atherosclerosis research has grown tremendously over the last forty years, shedding a great deal of light on the contributing factors and natural history of the disorder and enabling strategies for its treatment and prevention. Some of the greatest strides in this field in recent years have derived from advances in molecular biology techniques. These strides were chosen for emphasis in the most recent Princess Lilian symposium, whose proceedings this volume represents. Historically, the Princess Lilian meetings have been small ones aimed at bringing together investigators from diverse specialties to discuss a particular subject. The most recent meeting was no exception and included clinicians, clinical investigators, and research­ ers in basic science. The symposium began with an extensive review of coronary morphopathological findings in patients who died of coronary heart disease. Any rational hypothesis of atherogenesis must take into account clinical findings, and any attempt to bridge the gap between experimental laboratory findings and studies in man is highly desirable. Three chapters focus on endothelial injury: one on the nitric oxide pathway in physiology and pathology, a second on the activation of endothelial cells, and a third on the monocyte and endothelial injury. Still another chapter examines growth factors, in particular the fibroblast growth factor in atherogenesis.

Editors and Affiliations

  • The Methodist Hospital and Baylor College of Medicine, Houston, USA

    Antonio M. Gotto

Bibliographic Information

  • Book Title: Cellular and Molecular Biology of Atherosclerosis

  • Editors: Antonio M. Gotto

  • Series Title: Argenteuil Symposia

  • DOI: https://doi.org/10.1007/978-1-4471-1909-8

  • Publisher: Springer London

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag London Limited 1992

  • Softcover ISBN: 978-1-4471-1911-1Published: 23 November 2011

  • eBook ISBN: 978-1-4471-1909-8Published: 06 December 2012

  • Series ISSN: 1431-004X

  • Edition Number: 1

  • Number of Pages: XVI, 180

  • Topics: Biochemistry, general, Cardiology, Human Physiology

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