Orthopaedic Problems in Inherited Skeletal Disorders

1. Front Matter

   Pages I-XVI

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2. Genetic Principles

   • Frank Horan, Peter Beighton

   Pages 1-4

3. The Investigation and General Management of Bone Dysplasias

   • Frank Horan, Peter Beighton

   Pages 5-11

4. Nomenclature and Terminology

   • Frank Horan, Peter Beighton

   Pages 12-17

5. Disorders of Epiphyses and Metaphyses with Predominant Epiphyseal Involvement

   • Frank Horan, Peter Beighton

   Pages 18-24

6. Disorders of the Epiphyses and Metaphyses with Predominant Metaphyseal Involvement

   • Frank Horan, Peter Beighton

   Pages 25-36

7. Disorders of the Epiphyses and Metaphyses with Major Vertebral Involvement

   • Frank Horan, Peter Beighton

   Pages 37-47

8. Generalised Decrease in Bone Density

   • Frank Horan, Peter Beighton

   Pages 48-55

9. Increased Bone Density

   • Frank Horan, Peter Beighton

   Pages 56-64

10. Craniotubular Dysplasias and Hyperostoses

    • Frank Horan, Peter Beighton

    Pages 65-73

11. Cranio-Facial Abnormalities

    • Frank Horan, Peter Beighton

    Pages 74-78

12. Vertebral Anomalies

    • Frank Horan, Peter Beighton

    Pages 79-85

13. Limb and Digital Anomalies

    • Frank Horan, Peter Beighton

    Pages 86-95

14. Mucopolysaccharidoses (MPS) and Other Storage Disorders

    • Frank Horan, Peter Beighton

    Pages 96-105

15. Abnormalities of Cartilage and Fibrous Tissue

    • Frank Horan, Peter Beighton

    Pages 106-120

16. Miscellaneous Disorders

    • Frank Horan, Peter Beighton

    Pages 121-138

17. Back Matter

    Pages 139-144

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Inherited skeletal disorders have a fascination for many medical and surgical disciplines. For the geneticist there is interest in the study of families and their inheritance of lesions. The paediatrician is concerned because most of the disorders present in childhood as a problem in clinical differential diagnosis. The radiologist is interested because of the manifest, multiple and curious bone changes that provide a challenge in diagnosis and classification. The orthopaedic surgeon is involved because they present a challenge in the management of the many and various lesions of the limbs and trunk. Most of the text books are slanted towards one or other aspect of the subject, depending upon the specialist interests of their author. Though informative to colleagues in their own discipline, the information which they contain is liable to be overwhelming in its complexity or unhelpful in its content for the orthopaedic surgeon or trainee. Frank Horan and Peter Beighton have aimed their admirable and concise monograph to help the orthopaedic surgeon-the one individual who is likely to be able to ameliorate the musculo-skeletal problems from which so many of the children and adults with these diseases suffer. In recent years, much more orthopaedic help has become available for dysplastics.

• Erbkrankheit
• Orthopädie
• Osteogenesis imperfecta
• bone
• cartilage
• childhood
• chromosome
• classification
• complexity
• diagnosis
• diseases
• genes
• genetics
• orthopedics
• sonography

• Cuckfield Hospital, Cuckfield Sussex, England

  Frank Horan

• Medical School and Groote Schuur Hospital, University of Cape Town, Cape, South Africa

  Peter Beighton

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