High-Throughput Analysis

1. Front Matter

   Pages i-xxiii

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2. Elements of High-Throughput Analysis in Combinatorial Materials Science

   1. Elements of High-Throughput Analysis in Combinatorial Materials Science

      • Radislav A. Potyrailo, Eric J. Amis

      Pages 1-13

3. Economic Impact of Combinatorial Materials Science on Industry and Society [1]

   1. Economic Impact of Combinatorial Materials Science on Industry and Society [1]

      • John D. Hewes

      Pages 15-30

4. Optical Imaging and Spectroscopy

   1. Front Matter

      Pages 31-31

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   2. Image Analysis for High-Throughput Materials Science

      • Alamgir Karim, Amit Sehgal, J. Carson Meredith, Alfred J. Crosby, Eric J. Amis

      Pages 33-56

   3. Laser-Induced Fluorescence Detection in High-Throughput Screening of Heterogeneous Catalysts

      • Hui Su, Edward S. Yeung

      Pages 57-76

   4. Spectroscopic Imaging in the Mid-Infrared Applied to High-Throughput Studies of Supported Catalyst Libraries

      • Steven S. Lasko, Reed J. Hendershot, Yu Fu, Mark-Florian Fellmann, Gudbjorg Oskarsdottir, Christopher M. Snively et al.

      Pages 77-91

   5. Linear Spatially Encoded Combinatorial Chemistry with Fourier Transform Library Analysis

      • Alan W. Schwabacher, Christopher W. Johnson, Peter Geissinger

      Pages 93-104

5. Separations and Mass Spectrometry

   1. Front Matter

      Pages 105-105

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   2. Separation Approaches Toward Rapid and Complex Molecular Characterization of Diverse Polymers

      • Miroslav Petro, Son Hoai Nguyen, Han-Ting Chang

      Pages 107-123

   3. High-Throughput Gas Chromatography and Mass Spectrometry for Heterogeneous Catalysis: Screening of Catalytic Activities and Selectivities

      • Pierre-Alain W. Weiss, Jens w. Saalfrank, Jens Scheidtmann, Wilhelm F. Maier, Hans-Werner Schmidt

      Pages 125-153

   4. Rapid Determination of Molecular Parameters of Synthetic Polymers Using Precipitation-Redissolution HPLC and a “Molded” Monolithic Column

      • David Sýkora, Frantisek Svec, Jean M. J. Fréchet, Miroslav Petro, Adam L. Safir

      Pages 155-186

   5. Ion Mobility/Time-of-Flight Analysis of Combinatorial Library Mixtures

      • Catherine A. Srebalus Barnes, David E. Clemmer

      Pages 187-216

6. Sensors and Sensor Arrays

   1. Front Matter

      Pages 217-217

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   2. Acoustic Wave Sensors for High-Throughput Screening of Materials

      • Radislav A. Potyrailo, William G. Morris, Ronald J. Wroczynski

      Pages 219-246

   3. High-Throughput Screening of Oxidation Catalysts with Gas Sensors

      • Yusuke Yamada, Tetsuhiko Kobayashi

      Pages 247-259

   4. Optical Sensing Methods in High-Throughput Screening

      • Kerstin Kröger, Michael Seidel, Günter Gauglitz

      Pages 261-288

   5. Combinatorial Study and High-Throughput Screening of Transparent Barrier Films using Chemical Sensors

      • Jaime C. Grunlan, Dennis Saunders, Jay Akhave, Mark Licon, Marcel Murga, Aaron Chavira et al.

      Pages 289-316

   6. Intrinsic Fiber-Optic Sensors for Spatially Resolved Combinatorial Screening

      • Peter Geissinger, Alan W. Schwabacher

      Pages 317-345

7. Analysis of Mechanical, Electrical, and Thermal Properties

   1. Front Matter

      Pages 347-347

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This book, edited by Potyrailo and Amis, addresses a new paradigm-shifting approach in the search for new materials-Combinatorial Materials Science. One way to consider such an approach is to imagine an adventurous chef who decides to look for new entrees by cooking food ingredients in many pots using different combinations in every pot, and boil­ ing, steaming, or frying them in various ways. Although most of the pots will not have the tastiest food ever devised, some recipes will taste intriguing, and some eventually will lead to a discovery of a new fascinating cuisine. Of course, having a skilled chef design the com­ binatorial formulation will certainly be helpful in ensuring a successful outcome. Similar to food, each engineering material is a complex product of its chemical composition, structure, and processing. Generally, each of these components matters---change one and you get another material. Most of these "new" materials will be less good than ones we use now since existing materials have been refined with the extensive work of scientists and engi­ neers. At the same time if one prepares diverse materials like our adventurous chef, chang­ ing material composition, processing conditions and time, etc. , some of these materials will be superior to existing ones and a few might represent breakout technology.

• alloy
• composite
• electrochemistry
• materials science
• polymer
• polymers
• spectroscopy

"This book should serve as a valuable resource for those graduate students, scientists, and engineers, who are interested in accelerating their research using combinatorial technologies."
(J.J. Hanak, Ph.D.)
"High-Throughput Analysis will serve as an invaluable resource for practitioners and new comers to the field. With the ingenuity and diligent efforts of scientists and engineers working in this field, I am convinced that combinatorial materials sciences will greatly enhance our understanding and ability to solve the problems of complex materials systems in the 21st century."
(X.D. Xiang, Ph.D.)
"With examples drawn from electronics, polymer chemistry, catalysis, biomaterials, metallurgy, and inorganic materials, this book reviews the state-of-the-art developments in analytical instrumentation that are critical to the success of combinatorial materials science. This book will be invaluable to industrial and academic scientists and engineers, as well as graduate students interested in the developments of sensors and other types of miniaturized analytical instrumentation for rapid characterization of materials on a combinatorial scale."
(Scott C. Donnelly, Senior VP, GE Global Research, Schenectady, NY)

• GE Global Research, Schenectady

  Radislav A. Potyrailo

• National Institute of Standards and Technology, Gaithersburg

  Eric J. Amis

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