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Emerging Therapeutic Targets in Ovarian Cancer

  • Book
  • © 2011

Overview

Editors:
  1. Stan Kaye

    1. Royal Marsden Hospital, Drug Development Unit, Institute of Cancer Research, Sutton, United Kingdom

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  2. Robert Brown

    1. , Department of Surgery and Cancer, Imperial College London, London, United Kingdom

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  3. Hani Gabra

    1. , Department of Surgery and Cancer, Imperial College, London, United Kingdom

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    You can also search for this editor in PubMed   Google Scholar

  4. Martin Gore

    1. , Department of Medicine, Royal Marsden Hospital, London, United Kingdom

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  • Discusses the progress in linking the biology of ovarian cancer with novel targets and innovative therapies entering clinical trials.

  • Provides an up-to-date perspective on successful therapeutic developments as a partnership between laboratory-based and clinical-based research scientists.

  • Identifies those areas of translational research which we believe have shown the most promise, or are likely to do so, in the treatment of ovarian cancer.

  • Includes supplementary material: sn.pub/extras

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Table of contents (13 chapters)

  1. Front Matter

    Pages i-xiii
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  2. Systemic Therapy for Ovarian Cancer, Current Treatment, Recent Advances, and Unmet Needs

    • Susana Banerjee, Michael A. Bookman, Martin Gore
    Pages 1-33

  3. Discovery of Novel Targets

    • John Farley, Michael J. Birrer
    Pages 35-50

  4. Novel Anti-angiogenic Therapies in Ovarian Cancer

    • Jurjees Hasan, Gordon Jayson
    Pages 51-72

  5. Targeting the AKT Pathway in Ovarian Cancer

    • Euan A. Stronach, Azadeh Cheraghchi-Bashi, Michelle Chen, Hani Gabra
    Pages 73-94

  6. Inhibition of the Src Oncogene: Therapeutic Potential in Ovarian Carcinoma

    • Liz Y. Han, Anil K. Sood
    Pages 95-107

  7. Tumour-Specific Synthetic Lethality: Targeting BRCA Dysfunction in Ovarian Cancer

    • Timothy A. Yap, Stan H. Kaye, Alan Ashworth, Andrew Tutt
    Pages 109-132

  8. Targeting Inflammatory Pathways in Epithelial Ovarian Cancer

    • Jermaine Coward, Frances Balkwill
    Pages 133-164

  9. Epithelial-to-Mesenchymal Transition and Cellular Membrane Receptors in Ovarian Cancer: Moving Forward in the Era of Molecularly Targeted Therapy

    • Lainie P. Martin, Julia J. Perkins, Russell J. Schilder
    Pages 165-187

  10. Epigenetic Therapies

    • Robert Brown, Nadine Chapman-Rothe, Ros Glasspool
    Pages 189-202

  11. Ovarian Cancer Immunology and Immunotherapy

    • Sadaf Ghaem-Maghami, Martin Gore
    Pages 203-221

  12. Ovarian Cancer Progenitor/Stem Cells: Therapeutic Potential

    • Susan K. Murphy, Andrew Berchuck
    Pages 223-244

  13. Potential for α-Folate Receptor-Targeted Treatment for Ovarian Cancer

    • Chau H.M. Ng, Ann L. Jackman
    Pages 245-258

  14. New Insights into Tubulin Binders

    • Carles Escriu, James D. Brenton
    Pages 259-278

  15. Back Matter

    Pages 279-291
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About this book



Editors and Affiliations

  • Royal Marsden Hospital, Drug Development Unit, Institute of Cancer Research, Sutton, United Kingdom

    Stan Kaye

  • , Department of Surgery and Cancer, Imperial College London, London, United Kingdom

    Robert Brown

  • , Department of Surgery and Cancer, Imperial College, London, United Kingdom

    Hani Gabra

  • , Department of Medicine, Royal Marsden Hospital, London, United Kingdom

    Martin Gore

Bibliographic Information

  • Book Title: Emerging Therapeutic Targets in Ovarian Cancer

  • Editors: Stan Kaye, Robert Brown, Hani Gabra, Martin Gore

  • DOI: https://doi.org/10.1007/978-1-4419-7216-3

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media, LLC 2011

  • Hardcover ISBN: 978-1-4419-7215-6Published: 24 November 2010

  • Softcover ISBN: 978-1-4899-8233-9Published: 27 November 2014

  • eBook ISBN: 978-1-4419-7216-3Published: 23 November 2010

  • Edition Number: 1

  • Number of Pages: XIII, 291

  • Topics: Cancer Research, Pharmacology/Toxicology

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