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Origin of Cancers

Clinical Perspectives and Implications of a Stem-Cell Theory of Cancer

  • Book
  • © 2010

Overview

Authors:
  1. Shi-Ming Tu

    1. M.D. Anderson Cancer Center, The University of Texas, Houston, USA

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  • Will bring new treatment modalities to the cancer patient.
  • The theory of a stem-cell origin of cancers may completely transform our current views and perspective about cancer.

Part of the book series: Cancer Treatment and Research (CTAR, volume 154)

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Table of contents (20 chapters)

  1. Front Matter

    Pages i-xviii
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  2. Introduction

    • Shi-Ming Tu
    Pages 1-5

  3. Cancer Myths

    • Shi-Ming Tu
    Pages 7-18

  4. History of Cancer

    • Shi-Ming Tu
    Pages 19-31

  5. Origin of Cancer

    • Shi-Ming Tu
    Pages 33-42

  6. Stem Cells

    • Shi-Ming Tu
    Pages 43-54

  7. Stem Cells and Cancer

    • Shi-Ming Tu
    Pages 55-66

  8. Cancer Stem Cells

    • Shi-Ming Tu
    Pages 67-81

  9. Cancer Niche

    • Shi-Ming Tu
    Pages 83-91

  10. Ontogeny and Oncology

    • Shi-Ming Tu
    Pages 93-102

  11. Diagnosis and Prognosis

    • Shi-Ming Tu
    Pages 103-114

  12. Cancer Targets

    • Shi-Ming Tu
    Pages 115-128

  13. Heterogeneity of Cancer

    • Shi-Ming Tu
    Pages 129-136

  14. Metastasis

    • Shi-Ming Tu
    Pages 137-146

  15. Cancer Immunity

    • Shi-Ming Tu
    Pages 147-159

  16. Drug Resistance

    • Shi-Ming Tu
    Pages 161-175

  17. Paradigm Shifts

    • Shi-Ming Tu
    Pages 177-186

  18. Experimental Proof

    • Shi-Ming Tu
    Pages 187-199

  19. Clinical Implications

    • Shi-Ming Tu
    Pages 201-214

  20. Curing Cancer

    • Shi-Ming Tu
    Pages 215-225
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Keywords

About this book

Précis This book is a treatise about the origin of cancers. I would like to convince readers that the basic tenets of the theory of a stem-cell origin of cancers also constitute a unified theory of cancer. Stem-cell origin of normal (and cancer) cells: Vitruvian version Every truth passes through three stages before it is recognized. In the first it is ridiculed, in the second, it is opposed, in the third, it is regarded as self-evident. – Arthur Schopenhauer v vi Preface Every person has a unique story to tell. My story is about cancer. Cancer touches the lives of countless people. Often enough, it leaves indelible tracks. Many lives have been lost; others are forever changed. For those who confront this deadly scourge, there is a sense of urgency, if not of desperation. For those who face im- nent death, life becomes even more precious and carries a special meaning. As an oncologist, I am touched daily by cancer. I feel its inception, evolution, and aft- math. It seems as though we are fighting an incessant war against cancer at the front line in the trenches. This is my story about cancer. Some people are terrific storytellers. Others have incredible tales to tell.

Reviews

From the reviews:

“This concise book is written for a broad audience of basic science and clinical researchers interested in cancer biology, as well as those interested in the identification and directed differentiation of adult and embryonic stem cells. The author’s clear writing style will appeal to young scientists and nonexperts who are interested in … cancer stem-cell theory. … is captivating, fascinating, instructive, and well written. … The book is fun to read. … This is a welcome addition to the literature on cancer biology.” (Bruce A. Fenderson, Doody’s Review Service, July, 2010)

Authors and Affiliations

  • M.D. Anderson Cancer Center, The University of Texas, Houston, USA

    Shi-Ming Tu

Bibliographic Information

  • Book Title: Origin of Cancers

  • Book Subtitle: Clinical Perspectives and Implications of a Stem-Cell Theory of Cancer

  • Authors: Shi-Ming Tu

  • Series Title: Cancer Treatment and Research

  • DOI: https://doi.org/10.1007/978-1-4419-5968-3

  • Publisher: Springer New York, NY

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Science+Business Media, LLC 2010

  • Hardcover ISBN: 978-1-4419-5967-6Published: 19 May 2010

  • Softcover ISBN: 978-1-4614-2603-5Published: 01 July 2012

  • eBook ISBN: 978-1-4419-5968-3Published: 20 July 2010

  • Series ISSN: 0927-3042

  • Series E-ISSN: 2509-8497

  • Edition Number: 1

  • Number of Pages: CCXXXVII, 237

  • Number of Illustrations: 14 b/w illustrations, 15 illustrations in colour

  • Topics: Oncology, Cancer Research, Human Genetics

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