Crossroads between Innate and Adaptive Immunity III

1. Front Matter

   Pages i-x

   PDF

2. Is Transcription the Dominant Force During Dynamic Changes in Gene Expression?

   • Martin Turner

   Pages 1-13

3. MicroRNAs: Key Components of Immune Regulation

   • Donald T. Gracias, Peter D. Katsikis

   Pages 15-26

4. KIR/HLA: Genetic Clues for a Role of NK Cells in the Control of HIV

   • Lena Fadda, Galit Alter

   Pages 27-36

5. Natural Killer Cell Licensing During Viral Infection

   • Mark T. Orr, Lewis L. Lanier

   Pages 37-44

6. Bridging Innate NK Cell Functions with Adaptive Immunity

   • Emanuela Marcenaro, Simona Carlomagno, Silvia Pesce, Alessandro Moretta, Simona Sivori

   Pages 45-55

7. Control of Innate Immunity by Memory CD4 T Cells

   • Tara M. Strutt, K. Kai McKinstry, Susan L. Swain

   Pages 57-68

8. Strategies and Implications for Prime-Boost Vaccination to Generate Memory CD8 T Cells

   • Jeffrey C. Nolz, John T. Harty

   Pages 69-83

9. Blimp1: Driving Terminal Differentiation to a T

   • Annie Xin, Stephen L. Nutt, Gabrielle T. Belz, Axel Kallies

   Pages 85-100

10. A New Role for Myeloid HO-1 in the Innate to Adaptive Crosstalk and Immune Homeostasis

    • Vasiliki Koliaraki, George Kollias

    Pages 101-111

11. Impact of Differential Glycosylation on IgG Activity

    • Anja Lux, Falk Nimmerjahn

    Pages 113-124

12. Murine Model of Chronic Respiratory Inflammation

    • Amit A. Lugade, Paul N. Bogner, Yasmin Thanavala

    Pages 125-141

13. Incorporation of Innate Immune Effector Mechanisms in the Formulation of a Vaccine Against HIV-1

    • Aftab A. Ansari, Ann E. Mayne, Yoshiaki Takahashi, Kovit Pattanapanyasat

    Pages 143-159

14. Influenza Vaccines: What Do We Want and How Can We Get It?

    • Felix Geeraedts, Anke Huckriede

    Pages 161-174

This volume presents a collection of reviews derived from work presented at the Aegean Conference: “3rd Crossroads between innate and adaptive immunity” which occurred during September 27 - October 2, 2009 at the Minoa Palace Conference Center in Chania, Crete, Greece. This meeting was the third in a series, and assembled a team of scientists working on mechanisms by which the innate immune system of the host senses pathogens, the cellular and signaling networks that orchestrate the innate response and antigen presentation and adaptive immunity. The various facets of the innate response, including dendritic cells, T cells, B cells, NK cells, NK-T cells and the complement cascade during the host response to pathogens and tumors is only now starting to be elucidated. The respective fields that focus on these immune cells and molecules have tended to be relatively compartmentalized, and yet emerging evidence points to the interconnectedness of these facets in coordinating the innate response, and its subsequent impact on the adaptive response. The goal of this conference was to initiate cross-talk between these diverse immunological fields, and promote and facilitate discussion on the interactions between the innate immune response and the adaptive immune response and ultimately facilitate collaboration between these areas of study. Following on the footsteps of the outstanding success of its precursors, the “3rd Crossroads between Innate and Adaptive Immunity” Aegean Conference was highly successful in bringing together and connecting scientists and experts from around the world to address critical areas of Innate and Adaptive immunity.

• infectious diseases

• Emory Vaccine Center &, Yerkes National Primate Research Center, Emory University, Atlanta, USA

  Bali Pulendran

• College of Medicine, Department Microbiology & Immunology, Drexel University, Philadelphia, USA

  Peter D. Katsikis

• , Laboratory of Cellular Immunology, La Jolla Institute for Allergy and Immun, La Jolla, USA

  Stephen P. Schoenberger

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