Laser-Doppler Blood Flowmetry

1. Front Matter

   Pages i-xvii

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2. History of Laser-Doppler Blood Flowmetry

   • A. P. Shepherd

   Pages 1-16

3. Principles of Laser-Doppler Flowmetry

   • Robert F. Bonner, Ralph Nossal

   Pages 17-45

4. Medpacific’s LDV Blood Flowmeter

   • G. Allen Holloway Jr.

   Pages 47-56

5. Perimed’s LDV Flowmeter

   • Gert E. Nilsson

   Pages 57-72

6. TSI’s LDV Blood Flowmeter

   • John A. Borgos

   Pages 73-92

7. Innovations and Precautions

   • P. Åke Öberg

   Pages 93-108

8. Catheter Velocimeters

   • Michael D. Stern

   Pages 109-120

9. The Cutaneous Circulation

   • John M. Johnson

   Pages 121-139

10. Skin Pharmacology and Dermatology

    • Andreas J. Bircher, Richard H. Guy, Howard I. Maibach

    Pages 141-174

11. Plastic and Reconstructive Surgery

    • Per Hedén

    Pages 175-199

12. Peripheral Vascular Diseases

    • Bengt Fagrell

    Pages 201-213

13. Blood Flow in Skeletal Muscle

    • Karel Tyml, Richard J. Roman, Julian H. Lombard

    Pages 215-226

14. Gastrointestinal Blood Flow

    • J. W. Kiel, A. P. Shepherd

    Pages 227-250

15. Allergy and Respiratory Disease

    • Howard M. Druce

    Pages 251-264

16. Blood Flow in the Central and Peripheral Nervous Systems

    • Kishena C. Wadhwani, Stanley I. Rapoport

    Pages 265-288

17. Renal Blood Flow

    • Richard J. Roman

    Pages 289-304

18. Blood Flow in Bone

    • Sölve Hellem, E. Göran Salerud

    Pages 305-317

19. Cochlear Blood Flow

    • Josef M. Miller, Alfred L. Nuttall

    Pages 319-347

20. Retinal Blood Flow

    • Charles E. Riva, Benno L. Petrig, Juan E. Grunwald

    Pages 349-383

The dance along the artery The circulation on the lymph Are figured in the drift of stars. T. S. Eliot Die Methode ist alles. Carl Ludwig In physiology a spirit of finesse is required. Claude Bernard Armed with modern Doppler instrumentation, scientists can now quantify the red blood cell's "dance along the artery" as well as "the drift of stars. " In disciplines of science and medicine ranging from cardiology to astronomy, the Doppler principle now provides invaluable velo city measurements in the microcosm of capillary beds and in the cosmos. The newest appiication of the ubiquitous Doppler principle, laser-Doppler velocimetry, has been used to measure blood ftow in tissue for just a few years, but we perceived that, like most new techniques, the birth of laser-Doppler blood ftowmetry was not easy, nor was it likely to pass through infancy and reach maturity without difficulty. In physiology and medicine, better techniques for measur­ ing blood ftow are constantly in demand, but they often exhibit an unfortun­ ate boom-and-bust cyde: widespread acceptance and uncritical use are soon xiii xiv Preface followed by studies delineating the limits of the method's validity. The technique is then abandoned for the next more fashionable one, thus proving Ludwig's dictum that a given method is everything or nothing depending upon whether one can believe the data it yields.

• artery
• cardiology
• circulation
• physiology
• vascular disease

• Department of Physiology, University of Texas Health Science Center, San Antonio, USA

  A. P. Shepherd

• Department of Biomedical Engineering, University of Linköping, Linköping, Sweden

  P. Åke Öberg

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