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Recent Advances in Epilepsy Research

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 548)

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Table of contents (17 chapters)

  1. Front Matter

    Pages i-xvii
  2. Integrins, Synaptic Plasticity and Epileptogenesis

    • Christine M. Gall, Gary Lynch
    Pages 12-33
  3. Vascular Endothelial Growth Factor (VEGF) in Seizures:

    • Susan D. Croll, Jeffrey H. Goodman, Helen E. Scharfman
    Pages 57-68
  4. Plasticity Mechanisms Underlying mGluR-Induced Epileptogenesis

    • Robert K. S. Wong, Shih-Chieh Chuang, Riccardo Bianchi
    Pages 69-75
  5. Role of the GABA Transporter in Epilepsy

    • George B. Richerson, Yuanming Wu
    Pages 76-91
  6. GABA and Its Receptors in Epilepsy

    • Günther Sperk, Sabine Furtinger, Christoph Schwarzer, Susanne Pirker
    Pages 92-103
  7. Gap Junctions, Fast Oscillations and the Initiation of Seizures

    • Roger D. Traub, Hillary Michelson-Law, Andrea E. J. Bibbig, Eberhard H. Buhl, Miles A. Whittington
    Pages 110-122
  8. Functional Role of Proinflammatory and Anti-Inflammatory Cytokines in Seizures

    • Annamaria Vezzani, Daniela Moneta, Cristina Richichi, Carlo Perego, Maria G. De Simoni
    Pages 123-133
  9. Using the Immune System to Target Epilepsy

    • Deborah Young, Matthew J. During
    Pages 134-144
  10. Cortical Dysplasia and Epilepsy: Animal Models

    • Philip A. Schwartzkroin, Steven N. Roper, H. Jurgen Wenzel
    Pages 145-174
  11. Febrile Seizures and Mechanisms of Epileptogenesis: Insights from an Animal Model

    • Roland A. Bender, Celine Dubé, Tallie Z. Baram
    Pages 213-225
  12. The Tetanus Toxin Model of Chronic Epilepsy

    • Timothy A. Benke, John Swann
    Pages 226-238
  13. Brain Stimulation As a Therapy for Epilepsy

    • Jeffrey H. Goodman
    Pages 239-247

About this book

Epilepsy research has entered an exciting phase as advances in molecular analysis have supplemented in vitro and in vivo electrophysiologic and phenotypic characterization. Recent Advances in Epilepsy Research sets forth a series of chapter reviews by researchers involved in these advances. This volume is a composite profile of some exciting recent investigations in select areas of enquiry.
Key features: neurogenetics of seizure disorders, new developments in cellular and molecular neurobiology of seizure disorders, the role of growth factors in seizures, new advances in the roles of metabotropic glutamate receptors and GABA receptors and transporters, gap junctions, neuroimmunology of epilepsy, malformations of cortical development, neurogenesis, new animal models of epilepsy and the use of brain stimulation to treat epilepsy. This book should be of interest to a wide variety of audiences, including graduate students in neurobiology and related disciplines, neuroscientists, medical students, neurologists, neurosurgeons, and industry including pharmaceutical companies and medical device companies. There are many ideas in this book that will lead ingenious innovators in academia and industry to develop new and better therapies.

Editors and Affiliations

  • Department of Neurological Surgery, Moffitt Hospital, University of California at San Francisco, San Francisco, USA

    Devin K. Binder

  • Center for Neural Recovery and Rehabilitation Research, New York State Department of Health, Helen Hayes Hospital, West Haverstraw, USA

    Helen E. Scharfman

  • Departments of Pharmacology and Neurology, Columbia University, New York, USA

    Helen E. Scharfman

Bibliographic Information

  • Book Title: Recent Advances in Epilepsy Research

  • Editors: Devin K. Binder, Helen E. Scharfman

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4757-6376-8

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2004

  • Hardcover ISBN: 978-0-306-47860-4Published: 24 June 2004

  • Softcover ISBN: 978-1-4419-3418-5Published: 06 December 2010

  • eBook ISBN: 978-1-4757-6376-8Published: 14 March 2013

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XVIII, 248

  • Topics: Neurosciences, Neurology, Pharmacology/Toxicology

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access