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Single-Channel Recording

  • Book
  • © 1995

Overview

Editors:
  1. Bert Sakmann

    1. Department of Cell Physiology, Max-Planck-Institute for Medical Research, Heidelberg, Germany

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  2. Erwin Neher

    1. Department of Membrane Biophysics, Max-Planck-Institute for Biophysical Chemistry, Göttingen, Germany

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    You can also search for this editor in PubMed   Google Scholar

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Table of contents (22 chapters)

  1. Front Matter

    Pages i-xxvii
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  2. Introduction to Patch Clamping

    1. Front Matter

      Pages 1-1
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    2. A Practical Guide to Patch Clamping

      • Reinhold Penner
      Pages 3-30

    3. Tight-Seal Whole-Cell Recording

      • Alain Marty, Erwin Neher
      Pages 31-52

    4. Guide to Data Acquisition and Analysis

      • Stefan H. Heinemann
      Pages 53-91

  3. Methods

    1. Front Matter

      Pages 93-93
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    2. Electronic Design of the Patch Clamp

      • F. J. Sigworth
      Pages 95-127

    3. Low-Noise Recording

      • Klaus Benndorf
      Pages 129-145

    4. Voltage Offsets in Patch-Clamp Experiments

      • Erwin Neher
      Pages 147-153

    5. Techniques for Membrane Capacitance Measurements

      • Kevin D. Gillis
      Pages 155-198

    6. Patch-Pipette Recordings from the Soma, Dendrites, and Axon of Neurons in Brain Slices

      • Bert Sakmann, Greg Stuart
      Pages 199-211

    7. Patch Clamp and Calcium Imaging in Brain Slices

      • Jens Eilers, Ralf Schneggenburger, Arthur Konnerth
      Pages 213-229

    8. Fast Application of Agonists to Isolated Membrane Patches

      • Peter Jonas
      Pages 231-243

    9. Electrochemical Detection of Secretion from Single Cells

      • Robert H. Chow, Ludolf Von Rüden
      Pages 245-275

    10. Technical Approaches to Studying Specific Properties of Ion Channels in Plants

      • Rainer Hedrich
      Pages 277-305

    11. The Giant Membrane Patch

      • Donald W. Hilgemann
      Pages 307-327

    12. A Fast Pressure-Clamp Technique for Studying Mechanogated Channels

      • Don W. McBride Jr., Owen P. Hamill
      Pages 329-340

    13. Electrophysiological Recordings from Xenopus Oocytes

      • Walter Stühmer, Anant B. Parekh
      Pages 341-356

    14. Polymerase Chain Reaction Analysis of Ion Channel Expression in Single Neurons of Brain Slices

      • Hannah Monyer, Peter Jonas
      Pages 357-373

    15. Force Microscopy on Membrane Patches

      • J. K. Heinrich Hörber, Johannes Mosbacher, Walter Häberle
      Pages 375-393
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Keywords

About this book

Edited by the 1991 winners of the Nobel Prize in Physiology or Medicine, this Second Edition includes new chapters covering such applications as capacitance measurements; single-cell PCR measurements; whole-cell recording from brain slices in combination with imaging techniques; atomic force microscopy of cells and membranes attached to glass pipettes; and patch clamping.

Reviews

From reviews of the First Edition:

"A landmark in the field of membrane biophysics." (Science)

"A first-class laboratory guide...an indispensable reference." (Neuroscience)

Editors and Affiliations

  • Department of Cell Physiology, Max-Planck-Institute for Medical Research, Heidelberg, Germany

    Bert Sakmann

  • Department of Membrane Biophysics, Max-Planck-Institute for Biophysical Chemistry, Göttingen, Germany

    Erwin Neher

Bibliographic Information

  • Book Title: Single-Channel Recording

  • Editors: Bert Sakmann, Erwin Neher

  • DOI: https://doi.org/10.1007/978-1-4419-1229-9

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1995

  • Hardcover ISBN: 978-0-306-44870-6Published: 31 May 1995

  • Softcover ISBN: 978-1-4419-1230-5Published: 09 December 2009

  • eBook ISBN: 978-1-4419-1229-9Published: 03 October 2009

  • Edition Number: 2

  • Number of Pages: XXII, 700

  • Number of Illustrations: 50 b/w illustrations, 2 illustrations in colour

  • Topics: Animal Physiology, Biological and Medical Physics, Biophysics, Neurosciences

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