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  • © 2010

Muscle Gene Therapy

Editors:

  • This will be the first comprehensive volume on gene therapy in muscles, and most of the existing titles that touch on this or related subjects are published by Springer and listed above

  • Includes supplementary material: sn.pub/extras

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Softcover Book USD 199.99
Price excludes VAT (USA)
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  • Dispatched in 3 to 5 business days
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Table of contents (16 chapters)

  1. Front Matter

    Pages i-xv
  2. Animal Models for Inherited Muscle Diseases

    • Bruce F. Smith, Roberta Wrighten
    Pages 1-21
  3. In Utero Muscle Gene Transfer

    • Bhanu Munil Koppanati, Paula R. Clemens
    Pages 23-40
  4. Gene Therapy for the Respiratory Muscles

    • Gawiyou Danialou, Basil J. Petrof
    Pages 41-53
  5. Muscular Dystrophy Gene Therapy in Small Animal Models

    • Chunping Qiao, Xiao Xiao
    Pages 55-68
  6. Antisense-Mediated Exon Skipping for Duchenne Muscular Dystrophy

    • Annemieke Aartsma-Rus, Gert-Jan B van Ommen
    Pages 69-84
  7. RNAi Therapy for Dominant Muscular Dystrophies and Other Myopathies

    • Lindsay M. Wallace, Sara E. Garwick, Scott Q. Harper
    Pages 99-115
  8. Combinatorial Gene Therapy Strategies for Treating Muscular Dystrophies

    • Catherine E. Winbanks, Paul Gregorevic
    Pages 117-139
  9. Duchenne Cardiomyopathy Gene Therapy

    • Jin-Hong Shin, Brian Bostick, Deborah M. Fine, Yongping Yue, Dongsheng Duan
    Pages 141-162
  10. Systemic Gene Delivery for Muscle Gene Therapy

    • Dilip Garikipati, Jeffrey S. Chamberlain
    Pages 163-179
  11. Delivering Large Therapeutic Genes for Muscle Gene Therapy

    • Yi Lai, Yongping Yue, Brian Bostick, Dongsheng Duan
    Pages 205-218
  12. Muscle as a Metabolic Factory for Gene Therapy

    • Cathryn S. Mah, Christina A. Pacak, Barry J. Byrne
    Pages 219-230
  13. Muscle as a Target for Genetic Vaccine

    • Yan Zhi, Guangping Gao
    Pages 231-247
  14. Combining Stem Cells and Exon Skipping Strategy to Treat Muscular Dystrophy

    • Mirella Meregalli, Andrea Farini, Yvan Torrente
    Pages 249-256
  15. Back Matter

    Pages 269-275

About this book

Muscle disease represents an important health threat to the general population. There is essentially no cure. Gene therapy holds great promise to correct the genetic defects and eventually achieve full recovery in these diseases. Significant progresses have been made in the field of muscle gene therapy over the last few years. The development of novel gene delivery vectors has substantially enhanced specificity and efficiency of muscle gene delivery. The new knowledge on the immune response to viral vectors has added new insight in overcoming the immune obstacles. Most importantly, the field has finally moved from small experimental animal models to human patients. This book will bring together the leaders in the field of muscle gene transfer to provide an updated overview on the progress of muscle gene therapy. It will also highlight important clinical applications of muscle gene therapy.

Editors and Affiliations

  • Molecular Microbiology & Immunology, University of Missouri, Columbia, U.S.A.

    Dongsheng Duan

Bibliographic Information

Buy it now

Buying options

Softcover Book USD 199.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access