Overview
Will discuss how integrins and extracellular matrix components control cancer initiation, progression and metastasis
Includes supplementary material: sn.pub/extras
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Table of contents (12 chapters)
Keywords
About this book
Cancer was thought to originate from alterations in intercellular signaling that resulted in the transformation of cells, their uncontrolled proliferation and metastasis. There is now an increasing body of evidence demonstrating that the surrounding matrix and cell-matrix interactions are also major players in this process. Cells adhere and receive signals from various extracellular matrices via transmembrane receptors, the best known of which are the heterodimeric glycoproteins, integrins.
Editors and Affiliations
Bibliographic Information
Book Title: Cell-Extracellular Matrix Interactions in Cancer
Editors: Roy Zent, Ambra Pozzi
DOI: https://doi.org/10.1007/978-1-4419-0814-8
Publisher: Springer New York, NY
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag New York 2010
Hardcover ISBN: 978-1-4419-0813-1Published: 14 December 2009
Softcover ISBN: 978-1-4899-8112-7Published: 28 November 2014
eBook ISBN: 978-1-4419-0814-8Published: 23 January 2010
Edition Number: 1
Number of Pages: XII, 314
Topics: Cancer Research, Cell Biology, Pharmacology/Toxicology