Overview
- Fundamentals of the aldol addition are presented as well as brand new developments in the field of stereoselective aldol additions
- The use of metal enolates, Lewis acids, Lewis bases and enzymes in current total syntheses of natural products is discussed in detail
- The tremendous success of organocatalyzed aldol additions is highlighted under the aspects of selectivity and practicability in total syntheses
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Table of contents (20 chapters)
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Front Matter
Keywords
About this book
Aldol Reactions provides a comprehensive up-to-date overview of aldol reactions including application of different metal enolates; catalytic aldol additions catalyzed by different Lewis acids and Lewis bases; enantioselective direct aldol additions; antibodies and enzyme catalyzed aldol additions and the recent aggressive development of organocatalyzed aldol additions.
The power of each method is demonstrated by several applications in total synthesis of natural products. The pros and cons of these methodologies with regard to stereoselectivity, regioselectivity and application in total synthesis of natural products are discussed. Great importance is set to the diverse possibilities of the manual of aldol reaction to install required configurations in complicated natural product synthesis.
Editors and Affiliations
Bibliographic Information
Book Title: Aldol Reactions
Editors: Rainer Mahrwald
DOI: https://doi.org/10.1007/978-1-4020-8701-1
Publisher: Springer Dordrecht
eBook Packages: Chemistry and Materials Science, Chemistry and Material Science (R0)
Copyright Information: Springer Science+Business Media B.V. 2009
Hardcover ISBN: 978-1-4020-8700-4Published: 20 May 2009
Softcover ISBN: 978-90-481-7958-9Published: 19 October 2010
eBook ISBN: 978-1-4020-8701-1Published: 15 May 2009
Edition Number: 1
Number of Pages: XI, 211
Topics: Industrial Chemistry/Chemical Engineering, Physical Chemistry, Organometallic Chemistry, Organic Chemistry