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Chemical Probes in Biology

Science at the Interface of Chemistry, Biology and Medicine

  • Book
  • © 2004

Overview

Authors:
  1. Philip J. Snodgrass

    1. Indiana University School of Medicine, USA

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Table of contents (9 chapters)

  1. Front Matter

    Pages i-xv
    Download chapter PDF

  2. Gene Structure, Regulation and Function

    • Philip J. Snodgrass
    Pages 1-6

  3. Synthesis, Processing and Assembly

    • Philip J. Snodgrass
    Pages 7-11

  4. Molecular and Kinetic Characteristics

    • Philip J. Snodgrass
    Pages 12-23

  5. Active Site and Other Essential Residues

    • Thomas Hurley
    Pages 24-48

  6. Molecular Pathology of OTC Deficiency

    • Philip J. Snodgrass
    Pages 49-84

  7. Animal Models of OTC Deficiency and Their Gene Therapy

    • Philip J. Snodgrass
    Pages 85-105

  8. Clinical and Laboratory Findings in OTC Deficiency

    • Philip J. Snodgrass
    Pages 106-149

  9. Diagnosis and Treatment of OTC Deficiency

    • Philip J. Snodgrass
    Pages 150-164

  10. Induction and Suppression of OTC and Urea Cycle Enzymes in Bacteria, Fungi and Mammals

    • Philip J. Snodgrass
    Pages 165-181

  11. Back Matter

    Pages 183-243
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Keywords

About this book

Ornithine Transcarbamylase: Basic Science and Clinical Considerations, written by a leading expert on OTC, for the first time assembles and analyzes more than 40 years of basic science and clinical research. It will be the definitive resource on the topic for pediatricians, geneticists, and internists who care for patients with OTC deficiency, as well as for basic scientists and genetic researchers who study the urea cycle in mammals and the arginine biosynthetic pathway in bacteria and fungi.

Authors and Affiliations

  • Indiana University School of Medicine, USA

    Philip J. Snodgrass

Bibliographic Information

  • Book Title: Chemical Probes in Biology

  • Book Subtitle: Science at the Interface of Chemistry, Biology and Medicine

  • Authors: Philip J. Snodgrass

  • DOI: https://doi.org/10.1007/978-1-4419-9062-4

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media Dordrecht 2004

  • Hardcover ISBN: 978-1-4020-7683-1Published: 30 November 2003

  • Softcover ISBN: 978-1-4613-4779-8Published: 01 February 2014

  • eBook ISBN: 978-1-4419-9062-4Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XVII, 243

  • Topics: Biochemistry, general, Human Genetics, Internal Medicine, Pediatrics

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