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Models, Mysteries, and Magic of Molecules

  • Conference proceedings
  • © 2008

Overview

  • Aspects of molecular behaviour, central to the understanding of chemical and life sciences, feature in this collection of structurally biased papers, ranging from a study of transition-metal complexes, through proteins and their interactions, polymorphism, quasicrystals, to life in extreme environments
  • Highlights the need to identify common criteria for understanding the molecular basis of life
  • Includes supplementary material: sn.pub/extras

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Table of contents (20 papers)

Keywords

About this book

Molecules have for a long time been of central importance in chemistry as the basis on which all new products and materials have been designed, developed and interpreted. Since the discovery and characterization of active biomolecules, biology has also been transformed into a molecular science. With the new developments of molecular devices, single-molecule spectroscopy, time-resolved x-ray diffraction and the study of mass-selected clusters in molecular beams, materials science and electronics may move in the same direction.

The understanding of molecules and the dynamics of their transition between isolated and assembled states rests on three pillars: structure, activity and function. Enormous progress has been made in the experimental study of molecules by diffraction and spectroscopic analysis, directed at all three of the basic aspects. In the process molecular scientists have developed efficient working models in terms of which to design and interpret their experiments. A vital feature of such models is an understanding of intra- and intermolecular cohesion and assembly, or chemical bonding. One challenging aspect is that the working models of chemistry are notoriously difficult to reduce to the fundamental theories of the physical sciences.

The Indaba 5 meeting, held in South Africa during August 2006, was aimed at the progress that is being made to achieve first-principle understanding of molecular science: structure and dynamics (that includes bonding), activity and function. An interdisciplinary international team of experts came together to document and to probe various aspects of these fundamental questions and their startling conclusions confirm the need for a fresh look at the physical sciences with a view to better understand the mysteries and magic of molecules.

This book explores the common ground to guide chemists, biologists, crystallographers, spectroscopists and theorists into a deeper recognition of their individual relevance towards painting a holistic picture of scientific endeavour. This effort to stimulate interest in multidisciplinary research is rare, if not unique.

Reviews

From the reviews: “A book that will probably appeal more to chemists … is the result of an International Union of Crystallography Indaba workshop held in South Africa in August 2008. … The book is nicely divided into four sections, Methods, Mysteries, Magic, and Models, each with five chapters. … starts with a detailed, nicely illustrated, Raman spectroscopy study of life in extreme environments.” (Gary L. Long and Fernande Grandjean, Belgian Physical Society Magazine, Issue 1, 2010)

Editors and Affiliations

  • University of Pretoria, South Africa

    Jan C.A. Boeyens

  • Universidad de Costa Rica, Costa Rica

    J.F. Ogilvie

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