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DNA Methylation, Epigenetics and Metastasis

  • Book
  • © 2005

Overview

Editors:
  1. Manel Esteller

    1. Spanish National Cancer Centre (CNIO), Madrid, Spain

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  • First description of the epigenetic events involved in metastasis
  • Best experts in the field of DNA methylation in cancer
  • Right combination of theory and applications
  • Most updated bibliography
  • Most novel description of drugs targeting epigenetics in metastasis

Part of the book series: Cancer Metastasis - Biology and Treatment (CMBT, volume 7)

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-xi
    Download chapter PDF

  2. How CpG Island Hypermethylation Leads to Cancer Dissemination: The Sounds of Silence for Tumor and Metastasis Suppressor Genes

    • Manel Esteller
    Pages 1-8

  3. A Mouse Skin Multistage Carcinogenesis Model That Unmasks Epigenetic Lesions Responsible for Metastasis

    • Mario F. Fraga, Manel Esteller
    Pages 9-25

  4. CpG Island Hypermethylation and Lung Cancer Invasion and Metastasis

    • Ubaradka G. Sathyanarayana, Adi F. Gazdar
    Pages 27-43

  5. CpG Island Hypermethylation Changes during Prostate Cancer Progression and Metastasis

    • Srinivasan Yegnasubramanian, William G. Nelson
    Pages 45-79

  6. CpG Island Hypermethylation in Breast Cancer Progression and Metastasis

    • Paola Parrella
    Pages 81-132

  7. Epigenetic Dysregulation of Maspin (SerpinB5) in Cancer Invasion and Metastasis

    • Bernard W. Futscher, Frederick E. Domann
    Pages 133-155

  8. Epigenetic Regulation of the E-Cadherin Cell-Cell Adhesion Gene

    • Héctor Peinado, Amparo Cano
    Pages 157-190

  9. Epigenetic Disruption of the SLIT-ROBO Interactions in Human Cancer

    • Ashraf Dallol, Rachel E. Dickinson, Farida Latif
    Pages 191-214

  10. Molecular Mechanisms of the Metastasis-Associated Gene Family of Coregulators: Role in Cancer and Invasion

    • Seetharaman Balasenthil, Rakesh Kumar
    Pages 215-230

  11. The Molecular Mechanisms for Breast Cancer Metastasis Suppressor 1 Action in Cancer Metastasis

    • Rajeev S. Samant, Lalita A. Shevde
    Pages 231-242

  12. Mechanisms of DNA Demethylating Drugs Against Cancer Progression

    • Zunyan Dai, Kavitha Kosuri, Gregory A. Otterson
    Pages 243-267

  13. Histone Deacetylase Inhibitors: Novel Targeted Anti-Cancer Agents

    • Paul Marks, William Kevin Kelly
    Pages 269-305

  14. Back Matter

    Pages 307-310
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Keywords

Editors and Affiliations

  • Spanish National Cancer Centre (CNIO), Madrid, Spain

    Manel Esteller

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