Skip to main content
  • Reference work
  • Feb 2005

Handbook of Hydroxyacetophenones

Preparation and Physical Properties

Editors:

  • Each entry includes basic identification information including the Chemical Abstracts Service Registry Number (CAS RN), molecule name, molecular formula, and molecular weight: all critical nomenclature
  • The only resource covering this quantity and depth of information on physical properties and syntheses on a wide range of hydroxyketones
  • Powerful tool for the synthesis of intermediates of specialty polymers, pharmaceuticals and fine chemicals
  • 3000 hydroxyacetophenones covered and approximately 3500 references
  • Includes supplementary material: sn.pub/extras

This is a preview of subscription content, log in via an institution to check for access.

Table of contents (12 entries)

  1. Front Matter

    Pages i-xiv
  2. Compounds derived from acetic acid

    • Robert Martin
    Pages 3-554
  3. Compounds derived from halogenoacetic acids

    • Robert Martin
    Pages 555-648
  4. Compounds derived from aminoacetic acids

    • Robert Martin
    Pages 649-673
  5. Compounds derived from alkoxyacetic acids

    • Robert Martin
    Pages 674-702
  6. Compounds derived from aryloxyacetic acids

    • Robert Martin
    Pages 703-718
  7. Compounds derived from hydroxyacetic acids

    • Robert Martin
    Pages 719-730
  8. Compounds derived from nitroacetic acids

    • Robert Martin
    Pages 742-744
  9. Compounds derived from arylacetic acids

    • Robert Martin
    Pages 745-873
  10. Back Matter

    Pages 459-555

About this book

Third Edition entitled Aromatic Hydroxyketones: Preparation and Physical Properties to be published in 2010 as a 4-volume handbook set including:

  • Vol. 1: Hydroxybenzophenones
  • Vol. 2: Hydroxyacetophenones I
  • Vol. 3: Hydroxyacetophenones II
  • Vol. 4: Hydroxypropiophenones, Hydroxyisobutyrophenones, Hydroxypivalophenones and Derivatives

---------------

Hydroxyacetophenones constitute the starting material for a wide variety of syntheses in organic chemistry. They are versatile building blocks serving many different applications, such as specialty polymers, pharmaceuticals and fine chemicals. In this Handbook the diverse ways of obtaining over 3000 hydroxyacetophenones are described and their physico-chemical properties and spectroscopic data references are indicated.

The Handbook is presented in dictionary style, with a logical classification of the ketones, making the information easily available for consultation.

Ketones are classified methodically. They are thus easily accessible from three tables:
- the molecular formula index
- the chemical abstracts registry
- the usual names index.

This completely revised and enlarged edition includes:
- 10 additional chapters compared with the previous edition which had just 2 chapters
- an additional 1500 ketones
- updated information for ~1200 ketone entries
- the addition of di- and polyketones
- approximately 3500 references.

This Handbook is the reference on hydroxyacetophenones. It is a powerful synthesis tool for the researcher or industrial producers. Nowhere else are so many compounds covered or the physical properties and relevant syntheses provided. It provides a wide choice of hydroxyketones required to achieve syntheses based upon this range of intermediates.

Reviews

From the Foreword...
When Dr Martin asked me to write a Foreword for his new handbook, I was really enthusiastic. Indeed I met Dr Martin for the first time when joining the Institute Curie at the beginning of the 1990's to take the direction of the team of medicinal chemists. At that time Dr Martin was retired from the Sanofi company but was working at the bench from early in the morning to late in the evening like a young and brilliant student. He devoted all his time and energy to make complete the description of what constitutes the subject of his published handbooks. Tireless reader of a huge lot of periodicals, he collected, day after day, a large amount of data about the hydroxyacetophenones and the hydroxybenzophenones.
As a continuation of this already published two handbooks of both classes of compounds, Dr Martin now takes care of substituted hydroxyacetophenones. As these new collected compounds have been added to the unsubstituted analogs, one can say that this book constitutes and enlarged second edition of the first hydroxyacetophenone handbook. Not less than 3000 molecules and 3500 references can be found in this new volume. The presentation is the same as in the first two volumes with consistent data on the synthetic route or on the natural origin or each compound, and their physicochemical and spectroscopic characteristics available in the literature.
I am sure that, even at the internet era, this handbook will be helpful for the readers concerned by the use of these compounds in all the aspects of chemistry covering pharmaceutical, agrochemical, perfume, plastic preservatives domains or elaboration of small libraries of organic compounds for biological screening. Besides, consulting such a handbook is greatly facilitated by the presence of three comprehensive tables, including CAS number, official nomenclature and usual names. This will be helpful to the reader and I am sure that this book will meet the success it deserves.
Claude Monneret, Research Director at the CNRS

Bibliographic Information