Editors:
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 2152)
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Table of contents (36 protocols)
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Front Matter
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Overview of Cerebral Cavernous Malformations
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Front Matter
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Diagnosis and Treatment of Cerebral Cavernous Malformations
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Front Matter
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Animal and Cellular Models of Cerebral Cavernous Malformations
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Front Matter
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About this book
This volume provides experimental approaches aimed to characterize the Cerebral Cavernous Malformations (CCM) disease and to define the cellular and molecular mechanisms underlying this pathology. Chapters are divided into four sections providing a general overview of the natural history, epidemiology, and pathogenetic mechanisms of CCM disease, describing methods currently used for diagnosis and treatment, production and analysis of distinct cellular and animal models in which CCM can be studied, and different methodological approaches to study the mechanisms underlying the CCM onset and progression. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, Cerebral Cavernous Malformations (CCM): Methods and Protocols aims to ensure successful results in the further study of this complex disease and its pathophysiologic correlates.
Editors and Affiliations
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Department of Biotechnology, Chemistry and Pharmacy, University of Siena, SIENA, Italy
Lorenza Trabalzini, Federica Finetti
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Department of Clinical and Biological Sciences, School of Medicine and Surgery, University of Torino, ORBASSANO (TORINO), Italy
Saverio Francesco Retta
Bibliographic Information
Book Title: Cerebral Cavernous Malformations (CCM)
Book Subtitle: Methods and Protocols
Editors: Lorenza Trabalzini, Federica Finetti, Saverio Francesco Retta
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-0716-0640-7
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2020
Hardcover ISBN: 978-1-0716-0639-1Published: 11 June 2020
Softcover ISBN: 978-1-0716-0642-1Published: 11 June 2020
eBook ISBN: 978-1-0716-0640-7Published: 10 June 2020
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XV, 496
Number of Illustrations: 24 b/w illustrations, 62 illustrations in colour
Topics: Molecular Medicine