Overview
- Editors:
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David Murphy
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National University of Singapore, Republic of Singapore
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David A. Carter
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National University of Singapore, Republic of Singapore
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Table of contents (55 protocols)
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Introduction and Topical Reviews
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- David Murphy, David A. Carter
Pages 3-5
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- Kevin A. Ward, Colin D. Nancarrow
Pages 53-71
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Transgenesis in Invertebrate and Lower Vertebrate Species
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- Mark O’Connor, William Chia
Pages 75-85
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- Hong-Woo Khoo, Lay-Hong Ang, Hueh-Bin Lim
Pages 87-94
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Transgenesis in the Mouse
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- David Murphy, David A. Carter
Pages 111-114
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- David Murphy, David A. Carter, Duncan R. Smith
Pages 115-118
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- Duncan R. Smith, David Murphy
Pages 119-123
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About this book
Over the past twenty years, the disciplines of cellular and molecular biology have generated a bounty of information pertaining to the understanding of the structure and function of eukaryotic cells . It is now recognized that individual cells regulate their activities in response to a multitude of external signals ; that external signals, a- ing through a limited number of second messenger systems, modulate the cell's pattern of gene expression; and that the cohort of genes available for regulation is dependent upon the developmental history of the cell. Extrapolating these truths to the whole organism is a challenge that has been met by an increasing number of investigators . The wealth of information that molecular and cell biology has provided us with is now being integrated into an understanding of whole t- sues, organs, and organisms. Without such an integration, the molecular information will be nothing more than a confusing catalog of sequences and structures. Central to this project will be the app- cation of the powerful new techniques described in Transgenesis Techniques: Principles and Protocols .
Reviews
Such a book is precious...a must in every laboratory...-Cellular and Molecular Biology