Early Intervention in Psychotic Disorders

1. Front Matter

   Pages i-xiii

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2. Predicting Schizophrenia from Teachers’ Reports of Behaviour

   • P. B. Jones, T. J. Croudace

   Pages 1-28

3. Premorbid intervention

   • J. W. Carter, S. A. Mednick

   Pages 29-45

4. Epidemiology of Prodrome in Familial Schizophrenia

   • R. K. R. Salokangas, M. Heinimaa, T. Ilonen, T. Suomela, J. Korkeila, M. Plathin et al.

   Pages 47-69

5. The Prodromal Phase of Psychosis

   • H. Häfner, K. Maurer

   Pages 71-100

6. Recognition and Treatment of the Pre-psychotic Phase of Psychotic Disorders

   • Patrick D. McGorry, Lisa J. Phillips, Alison R. Yung

   Pages 101-122

7. Early Detection and Intervention Through Integration With Primary Health Services: The Buckingham Project

   • I. R. H. Falloon

   Pages 123-133

8. Instrument for the Assessment of Prodromal Symptoms and States

   • Thomas H. McGlashan, Tandy J. Miller, Scott W. Woods, Ralph E. Hoffman, Larry Davidson

   Pages 135-149

9. The Tips Project

   • Jan Olav Johannessen, Tor Ketil Larsen, Marthe Horneland, Inge Joa, Sigurd Mardal, Rune Kvebæk et al.

   Pages 151-166

10. Pharmacotherapy of First Episode Psychosis

    • Gary Remington, Shitij Kapur, Bob Zipursky

    Pages 167-180

11. Treatment in The Early Stages of Psychosis

    • Jan Libiger

    Pages 181-195

12. Family-Based Treatment in Prodromal and First-Episode Psychosis

    • William R. McFarlane

    Pages 197-230

13. Pathophysiology of Schizophrenia

    • John Kraus, Diana O. Perkins, Jeffrey A. Lieberman

    Pages 231-252

14. Back Matter

    Pages 253-289

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Multiple voices throughout the last century have preached the merits of various treatments for schizophrenia, ranging from cold baths to the currently accepted standards such as neuroleptic medication. Along with these ongoing treatments, there have been quiet commentaries, made mostly from the sidelines, suggesting the need to shift and refocus the way we think and talk about schizophrenia. Harry Stack Sullivan noted in 1927 that, 'The psychiatrist sees too many end states and deals professionally with too few of the pre­ psychotic" (Sullivan 192711994, p. 135). Similar thoughts have been echoed by purveyors of modem treatment for psychosis such as Thomas H. McGlashan: "Like others before me, I tried to make a difference . . . but like the others my efforts were largely in vain. I came upon the scene too late; most of the damage was already done" (McGlashan, 1996). Similar interest in the early phase of schizophrenia has developed across the globe and consolidated into a tentative, yet meaningful deliberation about the potential for prevention of psychotic illness through early identification and intervention. In the past decade, international support has grown from: Ian Falloon's prodromal intervention project in Great Britain (Falloon et aI. , 1996); Patrick McGorry's and Jane Edward's first episode psychosis program in Melbourne, Australia (McGorry et al.

• assessment
• epidemiology
• intervention
• neurobiology
• pathophysiology
• physiology
• psychiatric disorder
• psychotic disorder

• Department of Psychiatry, Yale University, New Haven, USA

  Tandy Miller, Thomas H. McGlashan

• Social Science Research Institute, University of California, Los Angeles, USA

  Sarnoff A. Mednick

• Psychiatric Center Prague, Prague, Czech Republic

  Jan Libiger

• Rogaland Psychiatric Hospital, Stavanger, Norway

  Jan Olav Johannessen

Policies and ethics