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Enzymes in Action Green Solutions for Chemical Problems

  • Book
  • © 2000

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Editors:
  1. Binne Zwanenburg

    1. Department of Organic Chemistry, NSR Institute for Molecular Structure, Design and Synthesis, University of Nijmegen, The Netherlands

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  2. Marian Mikołajczyk

    1. Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Łódź, Poland

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  3. Piotr Kiełbasiński

    1. Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Łódź, Poland

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Part of the book series: NATO Science Partnership Subseries: 1 (ASDT, volume 33)

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Table of contents (22 chapters)

  1. Front Matter

    Pages i-ix
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  2. Bio- and Chemo-Catalytic Deracemisation Techniques

    • Ulrike T. Strauss, Kurt Faber
    Pages 1-23

  3. Enzyme Assisted Routes to Bioactive Molecules

    • P. Andersch, F. Fazio, B. Haase, B. Jakob, M. P. Schneider
    Pages 25-42

  4. Molecular Basis for Empirical Rules that Predict the Stereoselectivity of Hydrolases

    • Alexandra N. E. Weissfloch, Romas J. Kazlauskas
    Pages 43-69

  5. Functional Group Transformations Mediated by Whole Cells and Strategies for the Efficient Synthesis of Optically Pure Chiral Intermediates

    • Nicholas J. Turner
    Pages 71-94

  6. Recent Advances on Bioreductions Mediated by Baker’s Yeast and Other Microorganisms

    • E. Santaniello, P. Ferraboschi, A. Manzocchi
    Pages 95-115

  7. Enzymatic Aminolysis and Ammonolysis Reactions

    • Vicente Gotor
    Pages 117-132

  8. Enantioselective Oxidations Catalyzed by Peroxidases and Monooxygenases

    • S. Colonna, N. Gaggero, C. Richelmi, P. Pasta
    Pages 133-160

  9. Hydrolytic Enzymes in The Synthesis of Non-Racemic Heteroorganic Compounds With A Stereogenic Centre on The Heteroatom

    • Piotr Kielbasiñski, Marian Mikolajczyk
    Pages 161-191

  10. Biodegradation of Hydrolyzed Chemical Warfare Agents by Bacterial Consortia

    • Joseph J. Defrank, Mark Guelta, Steven Harvey, Ilona J. Fry, James P. Earley, F. Stephen Lupton
    Pages 193-209

  11. Biodegradation Of Organophosphorus Nerve Agents by Surface Expressed Organophosphorus Hydrolase

    • W. Chen, R. D. Richins, P. Mulchandani, I. Kaneva, A. Mulchandani
    Pages 211-221

  12. Active Site Modifications of Organophosphorus Hydrolase for Improved Detoxification of Organophosphorus Neurotoxins

    • Janet K. Grimsley, Barbara D. Disioudi, Thomas R. Holton, James C. Sacchettini, James R. Wild
    Pages 223-242

  13. Hydrolysis of Organophosphorus Compounds by Bacterial Prolidases

    • Tu-Chen Cheng, Joseph J. Defrank
    Pages 243-261

  14. Ancillary Function of Housekeeping Enzymes: Fortuitous Degradation of Environmental Contaminants

    • R. Shane Gold, Melinda E. Wales, Janet K. Grimsley, James R. Wild
    Pages 263-286

  15. Field-Deployable Amperometric Enzyme Electrodes for Direct Monitoring of Organophosphate Nerve Agents

    • Ashok Mulchandani, Priti Mulchandani, Wilfred Chen, Joseph Wang, Liang Chen
    Pages 287-296

  16. Environmental Biocatalysis

    • Sergei Varfolomeyev, Sergei Kalyuzhnyi
    Pages 297-310

  17. Biocatalytic Synthesis of Alkaloids and Carbohydrates: An Update

    • Tomas Hudlicky
    Pages 311-321

  18. Bioconversion of Plant Materials: Lipids Proteins and Carbohydrates

    • B. Aha, M. Berger, B. Jakob, B. Haase, J. Hermann, G. Machmüller et al.
    Pages 323-345

  19. Enzymatic Regioselective Transformations in Natural Products

    • Miguel Ferrero, Vicente Gotor
    Pages 347-363

  20. Stereoselective Biocatalytic Formation of Cyanohydrins, Versatile Building Blocks for Organic Synthesis

    • Arne van der Gen, Johannes Brussee
    Pages 365-395
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Keywords

About this book

Enzymes in Action is a timely survey of a modern development in organic chemistry. It is clear that bioreagents demand that organic chemists think in a different way. If they do so, they will open up new avenues of exciting, new chemistry that will permit problems to be solved in an elegant way.
The first section covers the concepts necessary to understand enzymes in molecular operations. The second section covers heteroatom enzyme chemistry, with considerable attention being given to the use of enzymes in the detoxification of chemical warfare agents and their application in environmental problems. The final section highlights the strategic use of enzymes in organic chemistry.
It is clear that the term `green chemistry' is appropriate, since enzyme mediated processes occur under mild, environmentally benign conditions, and enzymes enable chemists to perform new chemical operations that would otherwise be difficult to achieve at all.

Editors and Affiliations

  • Department of Organic Chemistry, NSR Institute for Molecular Structure, Design and Synthesis, University of Nijmegen, The Netherlands

    Binne Zwanenburg

  • Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Łódź, Poland

    Marian Mikołajczyk, Piotr Kiełbasiński

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