This book gathers together chemical ideas which are important for understanding how drugs act and how new drugs may be developed. Students meet some of these ideas in courses in chemistry, biochemistry and pharmacology but in my experience they find it difficult to put together information often acquired in different years and from different departments; they need it set out in a book. I believe also that it helps if they can see how these ideas may be applied to numerical problems so I have included examples (with answers), many of which are taken from research work. These should therefore provide a chance for the student both to test his or her own understanding and to see the sort of results which form the bricks of which any experimental science is made. In all the problems the arithmetic takes less than ten minutes with a small calculator which has exponential functions and logarithms.

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Authors and Affiliations

University of Bristol, UK

R. B. Barlow

Bibliographic Information

Book Title: Quantitative Aspects of Chemical Pharmacology
Book Subtitle: Chemical Ideas in Drug Action with Numerical Examples
Authors: R. B. Barlow
DOI: https://doi.org/10.1007/978-1-4684-8332-1
Publisher: Springer New York, NY
eBook Packages: Springer Book Archive
Softcover ISBN: 978-0-7099-0300-0Published: 04 January 1979
eBook ISBN: 978-1-4684-8332-1Published: 06 December 2012
Edition Number: 1
Number of Pages: VI, 250
Topics: Pharmacology/Toxicology, Science, Humanities and Social Sciences, multidisciplinary

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Table of contents (5 chapters)

Front Matter

Measuring Drug Activity

Physicochemical Problems

The Size and Shape of Molecules

Chemical Processes where Size and Shape are Important

The Prediction of Drug Activity

Back Matter

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