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Cell Engineering

  • Book
  • © 1999

Overview

Editors:
  1. Mohamed Al-Rubeai

    1. School of Chemical Engineering, The University of Birmingham, Edgbaston, UK

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Part of the book series: Cell Engineering (CEEN, volume 1)

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-viii
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  2. Understanding the Translation Regulatory Mechanisms to Improve the Efficiency and the Specificity of Protein Production by the Cell Factory

    • P. Pierandrei-Amaldi, B. Cardinali, Anne-Catherine Prats, Hervé Prats, Bev. Osborne, Luc Paillard et al.
    Pages 1-37

  3. Modulation of Gene Expression by Ribozymes

    • Mara Szyrach, Olaf Heidenreich
    Pages 38-84

  4. High Yield Expression of Recombinant Proteins Requiring Proteolytic Maturation: Use of the Endoprotease Furin

    • M. Himmelspach, U. Schlokat, B. Plaimauer, F. G. Falkner, F. Dorner
    Pages 85-107

  5. Baculovirus Expression Vectors: Improving Virus-Infected Cell Viability and Recombinant Protein Secretion

    • R. D. Possee, L. McCarroll, C. J. Thomas, S. G. Mann, L. A. King
    Pages 108-121

  6. The Regulation of Apoptosis in Animal Cells

    • S. L. Mckenna, R. J. Carmody, T. G. Cotter
    Pages 122-161

  7. Inhibition of Apoptosis In Mammalian Cell Culture

    • A. J. Mastrangelo
    Pages 162-185

  8. Control of Mammalian Cell Proliferation as an Important Strategy in Cell Culture Technology, Cancer Therapy and Tissue Engineering

    • M. Fussenegger, J. E. Bailey
    Pages 186-219

  9. Development of an IRF-1 Based Proliferation Control System

    • P. P. Mueller, A. V. Carvalhal, J. L. Moreira, C. Geserick, K. Schroeder, M. J. T. Carrondo et al.
    Pages 220-238

  10. Factors Involved In The Cell Cycle Arrest Of Adult Rat Cardiomyocytes

    • Josef P. Magyar, Hans M. Eppenberger
    Pages 239-254

  11. Immortalization of Hepatocytes through Targeted Deregulation of the Cell Cycle

    • G. S. Jennings, M. Strauss
    Pages 255-287

  12. Back Matter

    Pages 288-302
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Keywords

About this book

Integrating advances in molecular biology into bioprocesses presents a continuous challenge to scientists and bioengineers. This series is conceived to help meet this challenge. It examines and assesses the feasibility of new approaches for the modification of cellular function such as gene expression, protein processing, secretion, glycosylation, immortalisation, proliferation, and apoptosis as well as the systematic study of the metabolic genotype-phenotype relationship. The series provides detailed coverage of the methodology for improving cellular properties of cells used in the production of biopharmaceuticals, gene and cell therapies and tissue engineering. It also seeks to explain the cellular mechanisms underlying in vitro physiological activity and productivity.
This volume, which is based on presentations at the `European Workshop on Animal Cell Engineering' held in Costa Brava, Spain, contains a collection of chapters relating to cellular function and modification by leading authorities in several different areas of basic research and the biopharmaceutical industry.

Editors and Affiliations

  • School of Chemical Engineering, The University of Birmingham, Edgbaston, UK

    Mohamed Al-Rubeai

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