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Sucralfate

From Basic Science to the Bedside

  • Book
  • © 1995

Overview

Editors:
  1. Daniel Hollander

    1. Dean’s Office, University of Kansas School of Medicine, Kansas City

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  2. Guido N. J. Tytgat

    1. Department of Gastroenterology-Hepatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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    You can also search for this editor in PubMed   Google Scholar

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Table of contents (33 chapters)

  1. Front Matter

    Pages i-xxiv
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  3. General Approach to Peptic Disease Therapy

    1. Ulcer Healing by Strengthening of Mucosal Defense

      • A. Tarnawski
      Pages 25-34

    2. History of the Development of Sucralfate

      • Akira Ishimori
      Pages 35-45

  4. Sucralfate: A Nonsystemic Site Protective Agent

    1. Chemistry of Sucralfate

      • Kiyoshige Ochi
      Pages 47-58

    2. Binding of Bile Acids by Sucralfate

      • W. F. Caspary
      Pages 59-70

  5. Mechanisms of Action of Sucralfate

    1. Binding of Sucralfate to the Mucosal Surface

      • Gerald P. Morris
      Pages 71-82

    2. Stimulation of Mucus Production

      • Clifford Tasman-Jones
      Pages 83-88

    3. Gastroduodenal Bicarbonate Secretion and its Response to Sucralfate

      • W. D. W. Rees
      Pages 89-101

    4. Effect of Sucrose Octasulfate on Isolated Gastric Cells

      • Michael R. Lucey, Tadataka Yamada
      Pages 103-109

    5. Effect on Gastric Surfactant

      • Brian A. Hills
      Pages 111-126

    6. Stimulation of Mucosal Prostaglandins by Sucralfate

      • Daniel Rachmilewitz
      Pages 127-132

    7. Sucralfate and Helicobacter pylori

      • J. A. Louw, G. O. Young, T. A. Winter, I. N. Marks
      Pages 133-140

    8. Sucralfate and Cell Proliferation

      • Hajime Kuwayama
      Pages 141-149

    9. Vascular Factors

      • Zsuzsa Sandor, Sandor Szabo
      Pages 151-162

    10. Sucralfate

      • Sandor Szabo, Stefano Kusstatscher, Zsuzsa Sandor, Miki Nagata, Judah Folkman, Y. Shing
      Pages 163-173

    11. Effects of Sucralfate on Growth Factor Availability

      • Stanislaw J. Konturek, Jan W. Konturek, Tomasz Brzozowski, Bronislaw L. Slomiany, Amelia Slomiany
      Pages 175-189

    12. Duodenal Ulcer Therapy, “Acid Rebound,” and Early Relapse

      • I. N. Marks, G. O. Young
      Pages 191-196

    13. Effect of Sucralfate on Experimental Ulcers

      • Susumu Okabe, Yoshiyasu Ogihara, Hiroyuki Koba
      Pages 197-207
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Keywords

About this book

International researchers summarize the current understanding of peptic disease and trace the development of a novel new drug for peptic disease therapy-sucralfate. Contributors present laboratory research along side data from clinical trials as well as from the practice of medicine. Articles discuss the history of sucralfate's development, mechanisms of action, clinical efficacy, and future directions for research. This volume will be of interest to scientists and clinicians working in gastroenterology and gastrointestinal physiology.

Editors and Affiliations

  • Dean’s Office, University of Kansas School of Medicine, Kansas City

    Daniel Hollander

  • Department of Gastroenterology-Hepatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

    Guido N. J. Tytgat

Bibliographic Information

  • Book Title: Sucralfate

  • Book Subtitle: From Basic Science to the Bedside

  • Editors: Daniel Hollander, Guido N. J. Tytgat

  • DOI: https://doi.org/10.1007/b102476

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1995

  • Hardcover ISBN: 978-0-306-44740-2Published: 31 January 1995

  • Softcover ISBN: 978-1-4757-7019-3Published: 24 August 2013

  • eBook ISBN: 978-0-585-32154-7Published: 07 July 2007

  • Edition Number: 1

  • Number of Pages: XXV, 366

  • Number of Illustrations: 51 b/w illustrations, 9 illustrations in colour

  • Topics: Gastroenterology, Hepatology, Internal Medicine, General Practice / Family Medicine, Pharmacology/Toxicology

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