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Selective Toxicity

The physico-chemical basis of therapy

  • Book
  • © 1981

Overview

Authors:
  1. Adrien Albert

    1. Research School of Chemistry, Australian National University, Canberra, Australia
      Department of Pharmacological Sciences, State University of New York, Stony Brook, USA

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-xiii
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  2. Topics of general interest

    1. Front Matter

      Pages 1-1
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    2. Selectivity in the service of man

      • Adrien Albert
      Pages 3-18

    3. Steps in the correlation of structure with biological action

      • Adrien Albert
      Pages 19-50

    4. Differences in distribution: the first principle of selectivity

      • Adrien Albert
      Pages 51-102

    5. Comparative biochemistry: the second principle of selectivity

      • Adrien Albert
      Pages 103-151

    6. Comparative cytology the third principle of selectivity

      • Adrien Albert
      Pages 152-179

    7. Chemotherapy: history and principles

      • Adrien Albert
      Pages 180-234

    8. Pharmacodynamics

      • Adrien Albert
      Pages 235-273

  3. Studies, in depth, of topics from part one

    1. Front Matter

      Pages 275-275
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    2. The nature of chemical bonds. Adsorption

      • Adrien Albert
      Pages 277-288

    3. Metabolites, enzymes, and metabolite analogues

      • Adrien Albert
      Pages 289-329

    4. Ionization

      • Adrien Albert
      Pages 330-384

    5. Metal-binding substances

      • Adrien Albert
      Pages 385-442

    6. The covalent bond in selective toxicity

      • Adrien Albert
      Pages 443-475

    7. Steric factors

      • Adrien Albert
      Pages 476-524

    8. Surface chemistry. The modification of membranes by surface-active agents

      • Adrien Albert
      Pages 525-542

    9. Biological activity unrelated to structure. Ferguson’s principle

      • Adrien Albert
      Pages 543-556

    10. The perfection of a discovery

      • Adrien Albert
      Pages 557-562

  4. Back Matter

    Pages 563-662
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Keywords

Authors and Affiliations

  • Research School of Chemistry, Australian National University, Canberra, Australia

    Adrien Albert

  • Department of Pharmacological Sciences, State University of New York, Stony Brook, USA

    Adrien Albert

Bibliographic Information

  • Book Title: Selective Toxicity

  • Book Subtitle: The physico-chemical basis of therapy

  • Authors: Adrien Albert

  • DOI: https://doi.org/10.1007/978-1-4899-6832-6

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Adrien Albert 1981

  • Softcover ISBN: 978-0-412-23650-1Published: 01 January 1981

  • eBook ISBN: 978-1-4899-6832-6Published: 22 November 2013

  • Edition Number: 6

  • Number of Pages: XIII, 662

  • Number of Illustrations: 50 b/w illustrations

  • Topics: Pharmacology/Toxicology

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