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The Golgi Apparatus

The First 100 Years

  • Book
  • © 2009

Overview

  • Presents a historical review of Golgi Apparatus research

  • Offers a summarization of the the modern era of Golgi Apparatus discovery including cell fractionation and biochemical analysis

  • Focuses on molecular biology and discusses cell growth contributions

  • Includes supplementary material: sn.pub/extras

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Table of contents (12 chapters)

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About this book

The Golgi Apparatus: The First 100 Years traces the first 100 years of Golgi apparatus discovery from the first published accounts from Pavia, Italy in 1898 to the Centenary Celebration in Pavia, Italy in 1998 and into the decade beyond. It is not intended, however, to be a comprehensive survey but rather to present the perspectives of the authors to summarize their contributions over the past 50 years in parallel with the modern era of Golgi apparatus discovery initiated in 1954 and made possible by the advent of the electron microscope. Included are methods of cell fractionation and biochemical analysis leading up to the present where efforts focus heavily on molecular biology. Topics where the authors and their colleagues have made substantial and/or pioneering contributions are emphasized including Golgi apparatus morphology and structural organization and function (especially in plants), the existence and importance of cisternal tubules, development of methods of plant and animal Golgi apparatus isolation and subfractionation, biochemical analyses of highly purified plant and animal Golgi apparatus fractions in comparison to equally highly pu- fied reference fractions.

Reviews

From the reviews:

“The volume represents a dense personal account of the activities in a very vivid field of biomedical inquiry. … it can provide an important basis for future historical analyses.” (Ariane Dröscher, History and Philosophy of the Life Sciences, Vol. 34 (4), 2012)

Editors and Affiliations

  • Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, West Lafayette, USA

    D. James Morré

  • College Station, College Station, USA

    Hilton H. Mollenhauer

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