Overview
- A useful reference to some of the most important aspects of systemic therapy resistance
- Allows those who are interested in breast cancer therapy to get a jump-start on critical issues in breast cancer therapeutic resistance
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 608)
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Table of contents (11 chapters)
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Front Matter
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Back Matter
Keywords
About this book
In Breast Cancer Chemosensitivity, a group of world leading experts review critical aspects of resistance to systemic therapy in breast cancer patients. Beginning with a clinical overview of the problem Breast Cancer Chemosensitivity moves on to focus on the latest findings of molecular mechanisms of drug resistance. These include in-depth discussions on multidrug resistance by P-glycoprotein and the multidrug resistance protein family, resistance to therapeutic agent-induced apoptosis, cell cycle deregulation, deregulation of DNA repair, loss of tumor suppressor genes, integrin-mediated adhesion, insulin-like growth factors, epidermal growth factor, and ErbB2 in modulating breast cancer response to systemic therapy, especially, certain chemotherapeutic agents. Breast Cancer Chemosensitivity provides an example of using novel approaches for chemosensitization of breast cancer cells that gives readers an idea about the future direction in breast cancer treatment.
Editors and Affiliations
Bibliographic Information
Book Title: Breast Cancer Chemosensitivity
Editors: Dihua Yu, Mien-Chie Hung
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-0-387-74039-3
Publisher: Springer New York, NY
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2007
Hardcover ISBN: 978-0-387-74037-9Published: 14 September 2007
Softcover ISBN: 978-1-4419-2542-8Published: 29 November 2010
eBook ISBN: 978-0-387-74039-3Published: 30 December 2009
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: XIII, 175
Topics: Oncology, Cancer Research, Biochemistry, general, Molecular Medicine, Cell Biology