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Hepatitis C Virus Disease

Immunobiology and Clinical Applications

  • Book
  • © 2008

Overview

Editors:
  1. Emilio Jirillo

    1. University of Bari and National Institute for Digestive Disease, Castellana Grotte, Italy

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  • The immunobiology of HCV and the IFN-induced modification of the immune response will be emphasized more clearly then it has ever been in any other publication

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Table of contents (12 chapters)

  1. Front Matter

    Pages I-XI
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  2. Innate Immunity in Type C Hepatitis

    • Tetsuo Takehara, Norio Hayashi
    Pages 1-15

  3. Mechanisms of Interferon Action and Resistance in Chronic Hepatitis C Virus Infection: Lessons Learned from Cell Culture Studies

    • Srikanta Dash, Sidhartha Hazari, Robert F Garry, Fredric Regenstein
    Pages 16-38

  4. Immunological Parameters Influencing Adaptive Immune Responses to the Hepatitis C Virus

    • Patrick Bertolino, Geoffrey W. McCaughan, David G. Bowen
    Pages 39-70

  5. Immune Responses Against the Hepatitis C Virus and the Outcome of Therapy

    • Paul Klenerman, Eleanor Barnes
    Pages 71-86

  6. Other Microbial Components Associated with Hepatitis C Virus Infection: Their Effects on Interferon-α/Ribavirin Treatment

    • Luigi Amati, Vittorio Pugliese, Emilio Jirillo
    Pages 87-105

  7. Interferon-Induced Effector Proteins and Hepatitis C Virus Replication

    • Michael Frese, Eva Dazert
    Pages 106-129

  8. Treatment of Chronic Hepatitis C with Different Genotypes

    • James Fung, Ching-Lung Lai, Man-Fung Yuen
    Pages 130-147

  9. Interferon Treatment of Hepatitis C Virus Infection: From Basic Biology to Clinical Application

    • Norihiro Furusyo, Masayuki Murata, Jun Hayashi
    Pages 148-167

  10. Interferon-Based Therapy for Hepatitis C Virus Infections

    • Ming-Lung Yu, Wan-Long Chuang
    Pages 168-191

  11. Treatment of Chronic Hepatitis C in “Difficult-to-Treat” Patients in the Clinical Setting

    • Ana Moreno, Rafael Bárcena, Carmen Quereda
    Pages 192-214

  12. Effects of Combined IFN-Alpha/Ribavirin Treatment in HCV Disease-Related Progression

    • Davide Festi, Francesca Lodato, Giuseppe Mazzella, Antonio Colecchia
    Pages 215-236

  13. Pegylated Interferons: Clinical Applications in the Management of Hepatitis C Infection

    • S. James Matthews, Christopher McCoy
    Pages 237-296

  14. Back Matter

    Pages 297-306
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Keywords

About this book

This comprehensive volume, written by experts in the field, emphasizes the most recent advances on the Hepatitis C virus infection (HCV) moving from basic research to clinical application. In spite of the numerous studies on HCV infection, its pathogenesis and medical treatment have not been fully explained. The first chapters of this volume analyize the full spectrum of immune responses to HCV taking into account either innate or adoptive immunity involvement. The volume also includes a series of contributions which explain the state of art of IFN-alpha treatment in HCV patients and the effectiveness of therapy also in relation to HCV genotypes. The use and applications of pegylated IFNs will also be discussed as well as the complicated HCV disease and its treatment. Hepatitis C Virus Disease: Immunobiology and Clinical Applications is an ideal volume for researchers, scientists, professionals, clinicians, physicians and graduate students in the fields of infectious disease, immunology, virology, microbiology, pharmacology and medicine.

Editors and Affiliations

  • University of Bari and National Institute for Digestive Disease, Castellana Grotte, Italy

    Emilio Jirillo

Bibliographic Information

  • Book Title: Hepatitis C Virus Disease

  • Book Subtitle: Immunobiology and Clinical Applications

  • Editors: Emilio Jirillo

  • DOI: https://doi.org/10.1007/978-0-387-71376-2

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer-Verlag New York 2008

  • Hardcover ISBN: 978-0-387-71375-5Published: 13 November 2007

  • Softcover ISBN: 978-1-4419-2438-4Published: 29 October 2010

  • eBook ISBN: 978-0-387-71376-2Published: 20 November 2007

  • Edition Number: 1

  • Number of Pages: XII, 308

  • Number of Illustrations: 37 b/w illustrations, 5 illustrations in colour

  • Topics: Immunology, Virology

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