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Interaction Between Neurons and Glia in Aging and Disease

  • Book
  • © 2007

Overview

Editors:
  1. João O. Malva

    1. University of Coimbra, Portugal

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  2. Ana Cristina Rego

    1. University of Coimbra, Portugal

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  3. Rodrigo A. Cunha

    1. University of Coimbra, Portugal

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  4. Catarina R. Oliveira

    1. University of Coimbra, Portugal

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  • The book is broken into three main sections to help guide the reader from the basic functional cross-talk between neuron and glia to brain pathology

  • Includes supplementary material: sn.pub/extras

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Table of contents (23 chapters)

  1. Front Matter

    Pages i-ix
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  2. Neuroimmunity and neuroinflammation

    1. Front Matter

      Pages 1-2
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    2. Inflammation and Neuronal Susceptibility to Excitotoxic Cell Death

      • João O. Malva, Liliana Bernardino
      Pages 3-35

    3. Microglial Cell Population Expansion Following Acute Neural Injury

      • M. Wirenfeldt, L. Dissing- Olesen, A. A. Babcock, R. Ladeby, M. B. Jensen, T. Owens et al.
      Pages 37-52

    4. Opposite Modulation of Peripheral Inflammation and Neuroinflammation by Adenosine A2A Receptors

      • Rodrigo A. Cunha, Jiang-Fan Chen, Michail V. Sitkovsky
      Pages 53-79

    5. Subventricular Zone Cells as a Tool for Brain Repair

      • Fabienne Agasse, Liliana Bernardino, João O. Malva
      Pages 81-108

  3. Signaling and inflammation in aging

    1. Front Matter

      Pages 109-110
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    2. Neuron-Glia Interaction in Homeostasis of the Neurotransmitters Glutamate and GABA

      • Arne Schousboe, Helle S. Waagepetersen
      Pages 111-120

    3. The Impact of an Imbalance Between Proinflammatory and Anti-inflammatory Influences on Synaptic function in the Aged Brain

      • Marina Lynch
      Pages 121-136

    4. Neurotrophin Signaling and Cell Survival

      • Bruno J. Manadas, Carlos V. Melo, João R. Gomes, Carlos B. Duarte
      Pages 137-172

    5. GDNF: a Key Player in Neuron-Glia Crosstalk and Survival of Nigrostriatal Dopaminergic Neurons

      • Emília P. Duarte, Ana Saavedra, Graça Baltazar
      Pages 173-192

    6. Molecular Pathways of Mitochondrial Dysfunction in Neurodegeneration: the Paradigms of Parkinson's and Huntington's Diseases

      • Ana Cristina Rego, Sandra Morais Cardoso, Catarina R. Oliveira
      Pages 193-219

    7. Zinc Homeostasis and Brain Injury

      • Stefano Sensi, Erica Rockabrand, Israel Sekler
      Pages 221-244

    8. Aging and Cognitive Decline: Neuroprotective Strategies

      • Frederico Simões do Couto, Alexandre de Mendonça
      Pages 245-268

  4. Neurodegeneration and inflammation in age related diseases

    1. Front Matter

      Pages 269-270
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    2. Inflammation and Apoptotic Pathways in the Peripheral Nervous System Related to Protein Misfolding

      • Maria João Saraiva
      Pages 271-280

    3. Neuroinflammation and Excitotoxicity in Neurobiology of HIV-1 Infection and AIDS: Targets for Neuroprotection

      • Marcus Kaul, Stuart A. Lipton
      Pages 281-308

    4. Neuroinflammation and Mitochondrial Dysfunction in Alzheimer's and Prion's Diseases

      • Paula Agostinho, Catarina R. Oliveira
      Pages 309-331

    5. Metal Ions and Alzheimer's Disease

      • Paul A. Adlard, Ashley I. Bush
      Pages 333-361

    6. Epilepsy, Brain Injury and Cell Death

      • Günther Sperk, Meinrad Drexel, Ramon Tasan, Anna Wieselthaler
      Pages 363-374
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Keywords

About this book

Interactions Between Neurons and Glia in Aging and Disease is a source of "reference reviews" and "concise overviews" of the functional cross-talk between neurons and glial cells, with a focus on microglia and inflammation in the aging brain and in neurological disorders. The scientific area covered by this book may be considered of key interest, and it is recognized, by the scientific community, as a major competitive area with critical implications for human health.

This book is organized in three main sections that are expected to guide the readers from the basic functional cross-talk between neuron and glia to brain pathology. The specific proposed sections are: 1) Neuroimmunity and Neuroinflammation; 2) Signalling and inflammation in aging; 3) Neurodegeneration and inflammation in age related diseases.

Editors and Affiliations

  • University of Coimbra, Portugal

    João O. Malva, Ana Cristina Rego, Rodrigo A. Cunha, Catarina R. Oliveira

Bibliographic Information

  • Book Title: Interaction Between Neurons and Glia in Aging and Disease

  • Editors: João O. Malva, Ana Cristina Rego, Rodrigo A. Cunha, Catarina R. Oliveira

  • DOI: https://doi.org/10.1007/978-0-387-70830-0

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer-Verlag US 2007

  • Hardcover ISBN: 978-0-387-70829-4Published: 23 August 2007

  • Softcover ISBN: 978-1-4419-4360-6Published: 04 November 2010

  • eBook ISBN: 978-0-387-70830-0Published: 09 August 2007

  • Edition Number: 1

  • Number of Pages: IX, 521

  • Topics: Neurosciences

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