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Genetically Engineered Mice for Cancer Research

design, analysis, pathways, validation and pre-clinical testing

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  • © 2012

Overview

  • Genetically-engineered mouse models for cancer research have become invaluable tools for studying cancer biology and evaluating novel therapeutic approaches
  • This volume focuses on state-of-the-art methods for generating, analyzing and validating such models for studying aspects of human cancer biology
  • Additionally, these models are emerging as important pre-clinical systems in which to test cancer prevention and therapeutic strategies in order to select compounds for testing in clinical trials
  • Includes supplementary material: sn.pub/extras

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Table of contents (28 chapters)

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About this book

Genetically-engineered mouse models for cancer research have become invaluable tools for studying cancer biology and evaluating novel therapeutic approaches. This volume focuses on state-of-the-art methods for generating, analyzing and validating such models for studying aspects of human cancer biology. Additionally, these models are emerging as important pre-clinical systems in which to test cancer prevention and therapeutic strategies in order to select compounds for testing in clinical trials.

Editors and Affiliations

  • , Laboratory Of Cancer Biology and Genetic, National Cancer Institute, Bethesda, USA

    Jeffrey E. Green

  • National Cancer Institute, Center for Cancer Research, National Institutes of Health, Bethesda, USA

    Thomas Ried

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