Overview
Addresses sampling of major elements of neural function at the cellular and molecular level that play important roles in development and aging
Stresses the dynamic features of neuronal responses to internal (developmental) cues and the more harmful external events (injury and disease)
Topics include neurotrophins, oligodendroglia, myelination, stress response, plasticity, misfolding proteins, and interventions to counteract aging-associated illness
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Table of contents (13 entries)
About this book
In the animal nervous system, a very high metabolic turnover, fragile but steep ionic gradients, and morphological and structural constraints - dictated by the necessity for prompt neuronal transmission of electrical impulses and necessary plasticity - result in a highly fragile organ system. Here, we address a small sampling of major constituents of neural function at the cellular and molecular level that play important roles in development and aging, two endogenous processes that embody features of allostasis or the dynamic shifts in set points for specific homeostatic mechanisms associated with development and aging. These chapters stress the dynamic features of neuronal responses to internal (developmental) cues or the more harmful external events (injury and disease) in a modern perspective.
Editors and Affiliations
Bibliographic Information
Book Title: Handbook of Neurochemistry and Molecular Neurobiology
Book Subtitle: Development and Aging Changes in the Nervous System
Editors: Abel Lajtha, J. Regino Perez-Polo, Steffen Rossner
DOI: https://doi.org/10.1007/978-0-387-32671-9
Publisher: Springer New York, NY
eBook Packages: Biomedical and Life Sciences, Reference Module Biomedical and Life Sciences
Copyright Information: Springer-Verlag US 2008
Hardcover ISBN: 978-0-387-32670-2Published: 06 June 2008
eBook ISBN: 978-0-387-32671-9Published: 23 February 2010
Edition Number: 3
Number of Pages: X, 324
Number of Illustrations: 48 b/w illustrations
Topics: Neurosciences