Authors:
- Comprehensive and up-to-date
- Detailed review of the field
- Includes supplementary material: sn.pub/extras
Part of the book series: Molecular Biology Intelligence Unit (MBIU)
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Table of contents (20 chapters)
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Front Matter
About this book
Epithelial phenotype is a dynamic stage of differentiation that can be modulated during several physiological or pathological events. The rapid conversion to a mesenchymal-like phenotype is called an epithelial-mesenchymal transition (EMT).
The Rise and Fall of Epithelial Phenotype is the first book to comprehensively introduce the concept of EMT. The first part of this volume describes main examples and models and explains their physiological relevance. These examples include hydra morphogenesis, gastrulation in mouse, drosophila and sea urchin, as well as neural crest cell migration and heart morphogenesis in vertebrates. Part two reviews in detail, specific EMT molecular pathways covering extracellular induction, transduction and transcription response and modulation of cell-cell adhesion structures. It emphasizes new specific pathways with potential medical applications. EMTs can also be linked to pathological events such as wound healing and cancer progression, as detailed in this section of the book.
Authors and Affiliations
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Génotypes et Phénotypes Tumoraux INSERM Bâtiment de Recherche en Cancerologie, CRLC Val d’Aurelle-Paul Lamarque, Montpellier Cedex, France
Pierre Savagner
Bibliographic Information
Book Title: Rise and Fall of Epithelial Phenotype
Book Subtitle: Concepts of Epithelial-Mesenchymal Transition
Authors: Pierre Savagner
Series Title: Molecular Biology Intelligence Unit
DOI: https://doi.org/10.1007/0-387-28671-3
Publisher: Springer New York, NY
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag US 2005
Hardcover ISBN: 978-0-306-48239-7Published: 13 July 2005
Softcover ISBN: 978-1-4419-3439-0Published: 01 December 2010
eBook ISBN: 978-0-387-28671-6Published: 05 July 2007
Series ISSN: 1431-0414
Edition Number: 1
Number of Pages: 248
Number of Illustrations: 99 b/w illustrations, 2 illustrations in colour
Topics: Cell Biology, Developmental Biology, Cancer Research