Overview
- Editors:
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Samir N. Khleif
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Vaccine Branch, National Cancer Institute, Bethesda Naval Hospital Bethesda, USA
King Hussein Cancer Center, Amman, Jordan
- Highlights the latest developments in tumor immunology from the perspective of leading authorities
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Table of contents (16 chapters)
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Basic Tumor Immunology
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- Laurence C. Eisenlohr, Jay L. Rothstein
Pages 3-36
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- Michael I. Nishimura, Jeffrey J. Roszkowski, Tamson V. Moore, Natasha Brasic, Mark D. Mckee, Timothy M. Clay
Pages 37-59
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- Michael Campoli, Soldano Ferrone, Arnold H. Zea, Paulo C. Rodriguez, Augusto C. Ochoa
Pages 61-88
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- Daniel F. Graziano, Olivera J. Finn
Pages 89-111
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Cancer Vaccine Development
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Front Matter
Pages 113-113
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- Jay A. Berzofsky, Sangkon Oh, Masaki Terabe
Pages 115-136
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- Andrew Y. Choo, Daniel K. Choo, J. Joseph Kim, David B. Weiner
Pages 137-156
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- Govind Ragupathi, John Gathuru, Philip Livingston
Pages 157-180
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- A. Grolleau, A. Sloan, J. J. Mulé
Pages 181-205
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- Hong-Ming Hu, Yiwei Chu, Walter J. Urba
Pages 207-225
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- Leisha A. Emens, R. Todd Reilly, Elizabeth M. Jaffee
Pages 227-245
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Vaccine-Enhancing Strategies
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Front Matter
Pages 247-247
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- Sameek Roychowdhury, Michael A. Caligiuri
Pages 249-266
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- Olivier Michielin, Jean-Sebastien Blanchets, Theres Fagerberg, Danila Valmori, Verena Rubio-Godoy, Daniel Speiser et al.
Pages 267-291
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- Shawn M. Jensen, Bernard A. Fox
Pages 293-336
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Clinical Trials Design
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Front Matter
Pages 337-337
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- Jan Casadei, Howard Z. Streicher, Jay J. Greenblatt
Pages 351-368
About this book
It all started with an observation. Edward Jenner, an English physician, observed that milkmaids who contracted cowpox were rarely victims of smallpox epidemic, a disease that in?icted a heavy toll on humankind with an estimate of 500 million victimsworldwide.In1796,Jennerinoculatedtheextracted?uidfromblistersonthe handofamilkmaidwhowasinfectedwithcowpoxintothearman8yearoldpeasant boy. After the boy recovered from a mild illness caused by this inoculation, Jenner exposed him to smallpox and to his delight the boy did not develop the disease. He published his work in 1798 in three publications titled “Vaccination Against smallpox”, where the term vaccination is derived from the Latin word “vacca” meaning cow. Jenner was recognized to be the father of modern immunology, and hisworkmarkedthecommencementofanewdawninmedicinethatledtothe1979 declaration by the World Health Organization (WHO) of the global eradication of smallpox. By the beginning of the 20th century, vaccines for typhoid fever, rabies, polio, plaque and diphtherias were in use, and nowadays we are equipped with effectivevaccinesagainstmorethan20infectiousdiseasessuchasmeningitis,rubella, whooping cough, rabies, and hepatitis B among others.
Editors and Affiliations
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Vaccine Branch, National Cancer Institute, Bethesda Naval Hospital Bethesda, USA
Samir N. Khleif
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King Hussein Cancer Center, Amman, Jordan
Samir N. Khleif
