Skip to main content
SpringerLink
Log in

Voltage-Gated Calcium Channels

  • Book
  • © 2005

Overview

Authors:
  1. Gerald W. Zamponi

    1. Department of Physiology and Biophysics, University of Calgary, Calgary, Canada

    View author publications

    You can also search for this author in PubMed   Google Scholar

  • This edited text serves as careful examination of calcium channels.
  • Voltage-Gated Calcium Channels is suitable for academic researchers at all levels in neuroscience, biophyisics, cell biology and drug discovery.
  • Includes supplementary material: sn.pub/extras

Part of the book series: Molecular Biology Intelligence Unit (MBIU)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (23 chapters)

  1. Front Matter

    Pages i-xiv
    Download chapter PDF

  2. Ca2+ Chemistry, Storage and Transport in Biologic Systems

    • Tashi G. Kinjo, Paul P. M. Schnetkamp
    Pages 1-11

  3. Monitoring Intracellular Ca2+ in Brain Slices with Fluorescent Indicators

    • Sean J. Mulligan, Brian A. MacVicar
    Pages 12-26

  4. A Brief History of Calcium Channel Discovery

    • Richard W. Tsien, Curtis F. Barrett
    Pages 27-47

  5. Biochemical Studies of Voltage-Gated Ca2+ Channels

    • William A. Catterall
    Pages 48-60

  6. Molecular Properties of Voltage-Gated Calcium Channels

    • Terrance P. Snutch, Jean Peloquin, Eleanor Mathews, John E. McRory
    Pages 61-94

  7. Role of β Subunits in Voltage-Gated Calcium Channel Functions

    • Thierry Cens, Sophie Restituito, Matthieu Rousset, Pierre Charnet
    Pages 95-112

  8. Distribution and Targeting Mechanisms of Voltage Activated Ca2+ Channels

    • Stefan Herlitze, Melanie D. Mark
    Pages 113-140

  9. The Calcium Channel and the Transmitter Release Site

    • Elise F. Stanley, Allen W. Chan
    Pages 141-153

  10. Determinants of G Protein Inhibition of Presynaptic Calcium Channels

    • Aparna Nirdosh, Gerald W. Zamponi
    Pages 154-167

  11. Phosphorylation-Dependent Regulation of Voltage-Gated Ca2+ Channels

    • Roger A. Bannister, Ulises Meza, Brett A. Adams
    Pages 168-182

  12. Ca2+-Dependent Modulation of Voltage-Gated Ca2+ Channels

    • Amy Lee, William A. Catterall
    Pages 183-193

  13. Voltage-Dependent Inactivation of Voltage Gated Calcium Channels

    • Mary T. An, Gerald W. Zamponi
    Pages 194-204

  14. Selective Permeability of Voltage-Gated Calcium Channels

    • William A. Sather
    Pages 205-218

  15. The Run-Down Phenomenon of Ca2+ Channels

    • Klaus J. F. Kepplinger, Christoph Romanin
    Pages 219-230

  16. Calcium Channels As Therapeutic Targets

    • Francesco Belardetti, Sian Spacey
    Pages 231-239

  17. Calcium Channelopathies

    • Nancy M. Lorenzon, Kurt G. Beam
    Pages 240-261

  18. The Molecular Basis of Ca2+ Antagonist Drug Action-Recent Developments

    • Jörg Striessnig, Jean-Charles Hoda, Edwin Wappl, Alexandra Koschak
    Pages 262-280

  19. Calcium Channel Block and Inactivation

    • Steffen Hering, Stanislav Sokolov, Stanislav Berjukow, Rainer Marksteiner, Eva Margreiter, Evgeni N. Timin
    Pages 281-293

  20. Block of Voltage-Gated Calcium Channels by Peptide Toxins

    • Christina I. Schroeder, Richard J. Lewis, David J. Adams
    Pages 294-308
Back to top

Keywords

About this book

oltage-gated calcium channels are essential mediators of a range of physiological functions, including the communication between nerve Vcells, the regulation of heart beat, muscle contraction, and secretion of hormones such as insulin. Consequently, these channels are critical phar­ macological targets in the treatment of a variety of disorders, such as epi­ lepsy, hypertension, and pain. Voltage-gated calcium channels have there­ fore been subject to intense study by numerous investigators over the past few decades, and an immense body of work has accumulated. In this book, we provide the first comprehensive overview of our current state of knowl­ edge concerning this exciting field of research. Leading off with a general review of calcium signaling and techniques to measure calcium channel ac­ tivity, the book delves into a provocative overview of the history of the cal­ cium channel field, contributed by one of the key pioneers in the field. Dr. Richard Tsien. This is followed by an in depth review of the biochemical and molecular biological characterization of calcium channel genes by Drs. Catterall and Snutch whose research has resulted in major advances in the calcium channel field. A number of chapters are dedicated towards various aspects of calcium channel structure and function, including channel gat­ ing, permeation, modulation and interactions with members of the exo- totic machinery—contributed by both established leaders and rising stars in the field.

Authors and Affiliations

  • Department of Physiology and Biophysics, University of Calgary, Calgary, Canada

    Gerald W. Zamponi

Bibliographic Information

Publish with us

Policies and ethics

Back to top

Search

Navigation