Overview
- Editors:
-
-
Samuel A. Tisherman
-
Department of Critical Care, University of Pittsburgh, Pittsburgh, USA
-
Fritz Sterz
-
Emergency Medicine, Medical University of Vienna, Vienna, Austria
- Fourth book in the Molecular and Cellular Biology of Critical Care Medicine series
- Emphasizes resuscitative hypothermia
- Global perspective on topic
Access this book
Other ways to access
Table of contents (16 chapters)
-
-
-
- Michael Holzer, Stephen A. Bernard, Fritz Sterz
Pages 11-24
-
- Hyung Soo Han, Midori A. Yenari
Pages 25-41
-
- Derk W. Krieger, Stefan Schwab, Lars P. Kammersgard
Pages 43-61
-
- Patrick M. Kochanek, Larry W. Jenkins, Robert S. B. Clark
Pages 63-86
-
-
- James D. Guest, W. Dalton Dietrich III
Pages 101-118
-
- Robert W. Hickey, Clifton W. Callaway
Pages 119-134
-
- Alistair J. Gunn, Laura Bennet
Pages 135-152
-
-
- Jesús Villar, Elena Espinosa
Pages 169-178
-
- Rajiv Jalan, Christopher Rose
Pages 179-190
-
- Sharon L. Hale, Robert A. Kloner, Shoichi Katada, Toshihiko Obayashi, Takeshi Ishii, Susumu Nakajima et al.
Pages 191-209
-
- Gernot Kuhnen, Niels Einer-Jensen, Samuel A. Tisherman
Pages 211-233
-
- Ram Nirula, Larry M. Gentilello
Pages 235-249
-
- Samuel A. Tisherman, Fritz Sterz, Wilhelm Behringer, Patrick Kochanek
Pages 251-252
-
Back Matter
Pages 253-258
About this book
Samuel A. Tisherman, MD', Fritz Sterz, MD~ '~niversit~ of Pittsburgh, Pittsburgh, PA, USA 2~edical University of Vienna, Vienna, Austria The use of hypothermia for a variety of therapeutic purposes has a long and erratic history. Hippocrates recommended the use of topical cooling to stop bleeding. Fay used cooling of the extremities for patients with tumors in the 1930s. It wasn't until the 1950s, when the effects of hypothermia on systemic oxygen metabolism became better defined, that systemic hypothermia became a commonly used modality, particularly for cardiac surgery. Hypothermia was used for protection (treatment before the insult) and preservation (treatment during the insult) of the heart and entire organism during planned operative ischemia. Shortly thereafter, attempts were made to use hypothermia for resuscitation (treatment after the insult) from cardiac arrest and for management of head trauma. At that time, it was felt that moderate hypothermia (28-32OC) was needed. This was difficult to achieve and manage. Multiple complications were noted. Consequently, therapeutic, resuscitative hypothermia lay dormant for many years while mild (32-35°C) to moderate hypothermia became common for many cardiothoracic and neurosurgical procedures. In the early 1990s, it was found that mild hypothermia, even after cardiac arrest, had benefit for the brain. Similar results were found with head trauma. This lead to a burst of enthusiasm for research into resuscitative hypothermia for a variety of insults, most of which have tissue ischemia as a major component.
Editors and Affiliations
-
Department of Critical Care, University of Pittsburgh, Pittsburgh, USA
Samuel A. Tisherman
-
Emergency Medicine, Medical University of Vienna, Vienna, Austria
Fritz Sterz
