Introduction to Molecular Medicine

1. Front Matter

   Pages i-xv

   PDF

2. Basics of Molecular Biology

   1. Front Matter

      Pages 1-1

      PDF

   2. The Human Genome

      • Dennis W. Ross

      Pages 3-21

   3. Gene Expression and Regulation

      • Dennis W. Ross

      Pages 22-34

   4. Genetic Engineering

      • Dennis W. Ross

      Pages 35-56

3. Molecular Approach to Disease

   1. Front Matter

      Pages 57-57

      PDF

   2. Infectious Diseases

      • Dennis W. Ross

      Pages 59-74

   3. Inherited Genetic Diseases

      • Dennis W. Ross

      Pages 75-92

   4. Immune System and Blood Cells

      • Dennis W. Ross

      Pages 93-107

   5. Cancer

      • Dennis W. Ross

      Pages 108-130

   6. Molecular Therapeutics

      • Dennis W. Ross

      Pages 131-143

   7. Conclusions

      • Dennis W. Ross

      Pages 144-145

4. Back Matter

   Pages 147-153

   PDF

This book continues the story of a new field called molecular medi­ cine. The first edition appeared 10 years ago in a previous millennium. At that time cloning a gene was cutting edge research; now gene cloning is a high school science fair project. The complete sequencing of the human genome was finished last year; cloning a human is a likely (and very controversial) event for 2002. The tools of molecular medicine have become very powerful and automated; DNA on a chip and microarrays allow us to probe large parts of the genome and its function. The speed of sequencing DNA has increased about 100,0- fold over the decade since the first edition of this book was published. Following the great improvements in technology, DNA and molecular research have a rapidly deepening impact on human medicine. Molec­ ular therapies including DNA vaccines, antisense, and gene transplan­ tation are undergoing clinical trials.

• gene expression
• genes
• infectious diseases
• molecular biology
• regulation

From the reviews:

"Well written... presented in a style that is eminently readable... Dr. Ross' book is recommended... of particular interest to pathology and clinical medicine residents." (Archives of Pathology, on the second edition)

"...will appeal to students and clinicians who will appreciate an introduction to this complicated field which unlike others, is easy and good fun to read." (Annals of Oncology, on the second edition)

• Department of Pathology, Forsyth Medical Center, Winston-Salem, USA

  Dennis W. Ross

• School of Medicine, Wake Forest University, Winston-Salem, USA

  Dennis W. Ross

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