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Nanobioelectronics - for Electronics, Biology, and Medicine

  • Book
  • © 2009

Overview

Editors:
  1. Andreas Offenhäusser

    1. Institute of Bio- and Nanosystems, Forschungszentrum Jülich, Jülich, Germany

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  2. Ross Rinaldi

    1. CNR Lecce, Ist. Nazionale di Fisica della Materia, National Nanotechnology Lab. (NNL), Lecce, Italy

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  • One of the first books on nanobiotechnology, this volume will survey the many results in this rapidly developing field

Part of the book series: Nanostructure Science and Technology (NST)

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Table of contents (14 chapters)

  1. Front Matter

    Pages i-xiv
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  2. DNA-Based Nanobioelectronics

    1. Front Matter

      Pages 5-8
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  3. Introduction

    1. Introduction

      • Andreas Offenhäusser, Ross Rinaldi
      Pages 1-3

  4. DNA-Based Nanobioelectronics

    1. Front Matter

      Pages 5-8
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    2. DNA for Electronics

      1. DNA-Mediated Assembly of Metal Nanoparticles: Fabrication, Structural Features, and Electrical Properties
        • Monika Fischler, Melanie Homberger, Ulrich Simon
        Pages 11-41
      2. DNA-Based Nanoelectronics
        • Rosa Di Felice
        Pages 43-79

    3. Electronics for Genomics

      1. DNA Detection with Metallic Nanoparticles
        • Robert Möller, Grit Festag, Wolfgang Fritzsche
        Pages 82-101
      2. Label-Free, Fully Electronic Detection of DNA with a Field-Effect Transistor Array
        • Sven Ingebrandt, Andreas Offenhäusser
        Pages 103-129

  5. Protein-Based Nanobioelectronics

    1. Front Matter

      Pages 131-135
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    2. Protein-Based Nanoelectronics

      1. Nanoelectronic Devices Based on Proteins
        • Giuseppe Maruccio, Alessandro Bramanti
        Pages 139-166
      2. S-Layer Proteins for Assembling Ordered Nanoparticle Arrays
        • Dietmar Pum, Uwe B. Sleytr
        Pages 167-180

    3. Electronics for Proteomics

      1. Electrochemical Biosensing of Redox Proteins and Enzymes
        • Qijin Chi, Palle S. Jensen, Jens Ulstrup
        Pages 182-209
      2. Ion Channels in Tethered Bilayer Lipid Membranes on Au Electrodes
        • Ingo Köper, Inga K. Vockenroth, Wolfgang Knoll
        Pages 211-223
      3. Fluorescent Nanocrystals and Proteins
        • Pier Paolo Pompa, Teresa Pellegrino, Liberato Manna
        Pages 225-254

  6. Cell-Based Nanobioelectronics

    1. Front Matter

      Pages 255-257
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    2. Neuron-Based Information Processing

      1. Spontaneous and Synchronous Firing Activity in Solitary Microcultures of Cortical Neurons on Chemically Patterned Multielectrode Arrays
        • T. G. Ruardij, W. L. C. Rutten, G. van Staveren, B. H. Roelofsen
        Pages 261-275
      2. Nanomaterials for Neural Interfaces: Emerging New Function and Potential Applications
        • Allison J. Beattie, Adam S. G. Curtis, Chris D. W. Wilkinson, Mathis Riehle
        Pages 277-286
      3. Interfacing Neurons and Silicon-Based Devices
        • Andreas Offenhäusser, Sven Ingebrandt, Michael Pabst, Günter Wrobel
        Pages 287-301

    3. Electronics for Cellomics

      1. Hybrid Nanoparticles for Cellular Applications
        • Franco Calabi
        Pages 304-330

  7. Back Matter

    Pages 331-337
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Keywords

About this book

The combination of biological elements with electronics is of great interest for many research areas. Inspired by biological signal processes, scientists and engineers are exploring ways of manipulating, assembling, and applying biomolecules and cells on integrated circuits, joining biology with electronic devices. The overall goal is to create bioelectronic devices for biosensing, drug discovery, and curing diseases, but also to build new electronic systems based on biologically inspired concepts. This research area called bioelectronics requires a broad interdisciplinary and transdisciplinary approach to biology and material science. Even though at the frontier of life science and material science, bioelectronics has achieved in the last years many objectives of scientific and industrial relevance, including aspects of electronics and biotechnology. Although the first steps in this field combined biological and electronic units for sensor applications (e. g. , glucose oxidase on an oxygen electrode), we see now many applications in the fields of genomics, proteomics, and celomics as well as electronics. This approach challenges both the researcher and the student to learn and think outside of their zones of comfort and training. Today, one can fabricate electrically active structures that are commensurate in size with biomolecules. The advancement of nanotechnology has influenced bioelectronics to a large extent.

Editors and Affiliations

  • Institute of Bio- and Nanosystems, Forschungszentrum Jülich, Jülich, Germany

    Andreas Offenhäusser

  • CNR Lecce, Ist. Nazionale di Fisica della Materia, National Nanotechnology Lab. (NNL), Lecce, Italy

    Ross Rinaldi

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