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  • © 2003

Foundations of Pharmacokinetics

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Table of contents (18 chapters)

  1. Front Matter

    Pages i-xvi
  2. Introduction

    Pages 1-3
  3. Models

    Pages 5-15
  4. Physical Quantities

    Pages 17-26
  5. Directed Graphs

    Pages 61-68
  6. Linear Graphs

    Pages 69-82
  7. Moments

    Pages 83-93
  8. Integral Equations

    Pages 95-111
  9. Matrix Equations

    Pages 113-125
  10. Non-Linear Models

    Pages 127-134
  11. Clearance

    Pages 135-141
  12. Turnover

    Pages 143-147
  13. Time Parameters

    Pages 161-170
  14. Conclusion

    Pages 179-180
  15. Back Matter

    Pages 181-228

About this book

This book has its origin in my experience as a teacher of pharmacokinetics in many universities in four different continents. It was not my intention to write a popular book; what distinguishes this one from many others on the same subject is its large use of algebra and calculus. For this I make no apologies; in fact a serious study of pharmacokinetics without the help of mathematics is, in my opinion, impossible. The exact definition of many pharmacokinetic quantities, even the most common, and the correct use of many equations, even the most simple, requires the constant use of mathematical language. On the other hand I have made a considerable effort to use only elementary algebra and elementary calculus, as commonly taught in most introductory university courses. For the few exceptions, when less common mathematical concepts were needed, I have supplied the necessary explanations in four appendices. The first three chapters are a general introduction to the scientific method. Chapters 4 to 12 show different specific methods to deal with pharmacokinetic pr- lems. There is considerable overlap among those chapters; this is intentional and its p- pose is to convince the reader that every problem can be solved in more than one way, including ways that were not mentioned in this book and that intelligent readers can find for their own pleasure. Chapters 13 to 17 show how different parameters of importance in pharmacokinetics can be exactly defined and measured.

Authors and Affiliations

  • University of Minnesota, Minneapolis

    Aldo Rescigno

Bibliographic Information

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access