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Cancer Cell Lines Part 1

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  • © 1999
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Overview

Editors:
  1. John R. W. Masters

    1. University College London, London, UK

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    You can also search for this editor in PubMed   Google Scholar

  2. Bernhard Palsson

    1. Dept. of Bioengineering, University of California, San Diego, USA

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Human Cell Culture (HUCC, volume 1)

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-x
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  2. Sarcomas

    • Beverly A. Teicher
    Pages 1-19
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  3. Neuroblastoma

    • Carol J. Thiele
    Pages 21-53
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  4. Ewing’s Sarcoma Family of Tumors

    • Frans van Valen
    Pages 55-85
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  5. Mesothelioma

    • Marjan A. Versnel
    Pages 87-105
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  6. Pancreatic Tumors

    • Takeshi Iwamura, Michael A. Hollingsworth
    Pages 107-122
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  7. Adrenal Cortex Tumors

    • William E. Rainey, James J. Mrotek
    Pages 123-135
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  8. Thyroid Gland Tumors

    • Thomas Hoelting
    Pages 137-148
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  9. Pituitary Gland Tumors

    • Leo J. Hofland, Steven W.J. Lamberts
    Pages 149-159
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  10. Salivary Gland Tumors

    • Mitsunobu Sato
    Pages 161-178
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  11. Esophageal Cancers

    • Yutaka Shimada
    Pages 179-212
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  12. Bladder Cancer

    • Ruth Knuechel, John R W Masters
    Pages 213-230
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  13. Renal Cell Cancer

    • Thomas Ebert, Aristoteles Anastasiadis, Neil H. Bander
    Pages 231-249
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  14. Skin Cancer (Non-Melanoma)

    • Petra Boukamp
    Pages 251-257
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  15. Melanoma: The Wistar Melanoma (WM) Cell Lines

    • Mei-Yu Hsu, David E. Elder, Meenhard Herlyn
    Pages 259-274
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  16. Melanoma: Brussels Melanoma Cell Lines

    • Francis Brasseur
    Pages 275-282
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  17. Melanoma: The Milan Melanoma Cell Lines

    • Andrea Anichini, Roberta Mortarini, Claudia Vegetti, Alessandra Molla, Alessandra Borri, Giorgio Parmiani
    Pages 283-292
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  18. Back Matter

    Pages 293-293
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Keywords

About this book

Continuous cell lines derived from human cancers are the most widely used resource in laboratory-based cancer research. The first 3 volumes of this series on Human Cell Culture are devoted to these cancer cell lines. The chapters in these first 3 volumes have a common aim. Their purpose is to address 3 questions of fundamental importance to the relevance of human cancer cell lines as model systems of each type of cancer: 1. Do the cell lines available accurately represent the clinical presentation? 2. Do the cell lines accurately represent the histopathology of the original tumors? 3. Do the cell lines accurately represent the molecular genetics of this type of cancer? The cancer cell lines available are derived, in most cases, from the more aggressive and advanced cancers. There are few cell lines derived from low grade organ-confined cancers. This gap can be filled with conditionally immortalized human cancer cell lines. We do not know why the success rate for establishing cell lines is so low for some types of cancer and so high for others. The histopathology of the tumor of origin and the extent to which the derived cell line retains the differentiated features of that tumor are critical. The concept that a single cell line derived from a tumor at a particular site is representative of tumors at that site is naïve and misleading.

Editors and Affiliations

  • University College London, London, UK

    John R. W. Masters

  • Dept. of Bioengineering, University of California, San Diego, USA

    Bernhard Palsson

Bibliographic Information

  • Book Title: Cancer Cell Lines Part 1

  • Editors: John R. W. Masters, Bernhard Palsson

  • Series Title: Human Cell Culture

  • DOI: https://doi.org/10.1007/0-306-46872-7

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media Dordrecht 1999

  • Hardcover ISBN: 978-0-7923-5143-6Published: 31 October 1998

  • Softcover ISBN: 978-94-017-3824-8Published: 13 November 2013

  • eBook ISBN: 978-0-306-46872-8Published: 11 April 2006

  • Series ISSN: 1389-2142

  • Edition Number: 1

  • Number of Pages: X, 293

  • Topics: Cancer Research, Cell Biology, Oncology, Internal Medicine

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